PIN1: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1f8a chain B
1i6c chain A
1i8g chain B
1i8h chain B
1nmv chain A
1nmw chain A
1pin chain A
1zcn chain A
2f21 chain A
2itk chain A
2kbu chain A
2kcf chain A
2lb3 chain A
2m8i chain A
2m8j chain A
2m9e chain A
2m9f chain A
2m9i chain A
2m9j chain A
2n1o chain A
2q5a chain A
2ruc chain A
2rud chain A
2ruq chain A
2rur chain A
2xp3 chain A
2xp4 chain A
2xp5 chain A
2xp6 chain A
2xp7 chain A
2xp8 chain A
2xp9 chain A
2xpa chain A
2xpb chain A
2zqs chain A
2zqt chain A
2zqu chain A
2zqv chain A
2zr4 chain A
2zr5 chain A
2zr6 chain A
3i6c chain A
3i6c chain B
3ik8 chain A
3ik8 chain B
3ikd chain A
3ikd chain B
3ikg chain A
3ikg chain B
3jyj chain A
3jyj chain B
3kab chain A
3kac chain A
3kac chain B
3kad chain A
3kaf chain A
3kag chain A
3kah chain A
3kai chain A
3kce chain A
3ntp chain A
3odk chain A
3oob chain A
3tc5 chain A
3tcz chain A
3tdb chain A
3wh0 chain A
4gwt chain A
4gwv chain A
4qib chain A
4tns chain A
4tns chain B
4tyo chain A
4tyo chain B
4u84 chain A
4u85 chain A
4u86 chain A
5b3w chain A
5b3w chain B
5b3x chain A
5b3y chain A
5b3z chain A
5b3z chain B
5b3z chain C
5b3z chain D
5bmy chain A
5gph chain A
5uy9 chain A
5vti chain A
5vtj chain A
5vtk chain A
6dun chain A
6dun chain B
6o33 chain A
6o34 chain A
6svc chain A
6sve chain A
6svh chain A
6vaj chain A
7aog chain P
7axn chain P
7ayf chain P
7az1 chain P
7az2 chain P
7bdp chain P
7bdt chain P
7bdy chain P
7bfw chain P
7bg3 chain P
7bgq chain P
7bgr chain P
7bgv chain P
7bgw chain P
7efj chain A
7efx chain A
7ekv chain A
7f0m chain A
7f0m chain B
7f0m chain C
7f0m chain D
7nif chain P
7nig chain P
7nj6 chain P
7nj8 chain P
7nja chain P
7nrk chain P
7nrl chain P
7oq9 chain P
7oqa chain P
7sa5 chain A
7suq chain A
7sur chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S41 WERPSGNS SSGGKNG 1 27 - - - - - - 27 - - - - - - - - - - - - - S42 ERPSGNSS SGGKNGQ 1 8 - - - - - - 8 - - - - - - - - - - - - - S71 HSQSRRPS SWRQEKI 1 36 - - - - - - 36 - - - - - - - - - - - - - S72 SQSRRPSS WRQEKIT 1 18 - - - - - - 18 - - - - - - - - - - - - - S98 GYIQKIKS GEEDFES 3 77 8 - 8 8 - - 53 - - - - - - - - - - - - - S105 SGEEDFES LASQFSD 3 24 - - 8 - - - 9 - - - - - - - - - 5 2 - - S111 ESLASQFS DCSSAKA 2 13 - - - - - - - - - - - - - - - - 4 1 6 2 S115 SQFSDCSS AKARGDL 2 21 - - - - - - 8 - - - - - - - - - - - 13 - T152 EMSGPVFT DSGIHII 6 338 66 - 46 36 - - - - - - 54 50 38 35 7 1 3 2 - - S154 SGPVFTDS GIHIILR 3 120 - - - - - - 82 - 17 11 5 5 - - - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S41 WERPSGNS SSGGKNG - - - - - - - - - - - S42 ERPSGNSS SGGKNGQ - - - - - - - - - - - S71 HSQSRRPS SWRQEKI - - - - - - - - - - - S72 SQSRRPSS WRQEKIT - - - - - - - - - - - S98 GYIQKIKS GEEDFES - - - - - - - - - - - S105 SGEEDFES LASQFSD - - - - - - - - - - - S111 ESLASQFS DCSSAKA - - - - - - - - - - - S115 SQFSDCSS AKARGDL - - - - - - - - - - - T152 EMSGPVFT DSGIHII -4.1e-6 - 0.2 - - - -8.2e-4 -3.1e-9 - - - S154 SGPVFTDS GIHIILR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S41
S42
S71
S72
S98
S105
S111
S115
T152
S154
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation CCRCC S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation COAD S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation GBM S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation HNSCC S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation LSCC S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation LUAD S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation OV S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation PDAC S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation UCEC S41 S42 S71 S72 S98 S105 S111 S115 T152 S154 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S41
S42
S71
S72
S98
S105
S111
S115
T152
S154
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S41
S42
S71
S72
S98
S105
S111
S115
T152
S154
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.