Protein: ENSP00000248594

PTPN12:: protein tyrosine phosphatase non-receptor type 12

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S19	QRVQAMKSPDHNGED	10	885	75	-	44	25	1	7	99	-	78	47	80	73	110	101	22	5	41	19	40	18
S83	KLTLKTPSQDSDYIN	10	814	63	-	34	22	17	10	90	-	80	46	63	58	71	64	35	7	64	28	59	3
S275	EMRTQRHSAVQTKEQ	5	358	17	-	-	-	-	-	18	-	-	-	14	12	91	83	-	-	89	34	-	-
T318	DGVNEINTENMVSSI	3	34	9	-	12	4	-	-	-	-	-	-	-	-	-	-	-	-	7	2	-	-
S323	INTENMVSSIEPEKQ	4	89	29	-	16	8	-	-	-	-	-	-	14	13	-	-	-	-	7	2	-	-
S324	NTENMVSSIEPEKQD	3	35	-	-	-	-	-	-	-	-	13	6	5	5	-	-	-	-	5	1	-	-
S332	IEPEKQDSPPPKPPR	10	1412	122	-	103	80	61	72	99	-	108	62	108	99	110	101	19	6	105	44	95	18
S342	PKPPRTRSCLVEGDA	10	1331	105	-	103	80	24	21	99	-	98	55	103	94	106	97	69	15	105	44	95	18
T367	HPVPPILTPSPPSAF	8	209	7	-	48	28	-	-	63	-	6	3	10	8	4	4	-	-	14	6	5	3
S369	VPPILTPSPPSAFPT	10	927	15	-	29	27	71	70	99	-	101	59	59	54	55	49	31	5	99	41	47	16

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S19	QRVQAMKSPDHNGED	7.6e-47	-	1.1e-10	-	-	4.2e-13	1.3e-5	2.3e-19	-	1.9e-7	3.3e-3
S83	KLTLKTPSQDSDYIN	0.32	-	2.1e-7	-	-	0.51	-5.8e-8	-0.84	-	0.046	-
S275	EMRTQRHSAVQTKEQ	2.3e-3	-	-	-	-	-	-	-0.02	-	3.3e-11	-
T318	DGVNEINTENMVSSI	-	-	-	-	-	-	-	-	-	-	-
S323	INTENMVSSIEPEKQ	-	-	-	-	-	-	-	-	-	-	-
S324	NTENMVSSIEPEKQD	-	-	-	-	-	-	-	-	-	-	-
S332	IEPEKQDSPPPKPPR	3.6e-63	-	4e-30	4.9e-3	-	8.3e-24	0.066	1.5e-10	-	1.3e-11	3.5e-7
S342	PKPPRTRSCLVEGDA	-0.11	-	1.1e-21	-0.92	-	1.8e-8	-8.2e-24	-5.7e-12	0.52	-0.59	-0.17
T367	HPVPPILTPSPPSAF	2.6e-4	-	2.6e-4	-	-	-	-	-	-	-	-
S369	VPPILTPSPPSAFPT	2.1e-3	-	0.038	6.9e-7	-	0.74	-3.5e-4	-0.7	-	0.017	0.018

Showing 1 to 10 of 49 rows

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000248594Gene: PTPN12

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000248594
Gene: PTPN12