CDC42EP1: CDC42 effector protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14 GRGAATMS LGKLSPV 3 103 - - - - - - - - - - 18 17 - - - - 33 15 18 2 S19 TMSLGKLS PVGWVSS 9 663 - - 25 23 5 4 99 - 52 32 50 46 34 31 61 16 96 41 48 - S25 LSPVGWVS SSQGKRR 9 293 67 - 12 10 5 4 9 - - - 43 39 26 25 7 1 14 5 23 3 S26 SPVGWVSS SQGKRRL 2 30 20 - - - - - - - - - 5 5 - - - - - - - - S27 PVGWVSSS QGKRRLT 8 296 8 - - - 6 3 81 - - - 5 5 8 7 7 1 56 23 68 18 T34 SQGKRRLT ADMISHP 10 715 53 - 31 22 42 48 99 - 73 45 34 33 17 17 20 5 105 44 15 12 S71 LSNHGGSS GSTHRSP 1 17 - - - - - - 17 - - - - - - - - - - - - - S73 NHGGSSGS THRSPRS 3 59 - - - - - - 26 - 11 6 - - - - 14 2 - - - - S77 SSGSTHRS PRSFLAK 3 113 - - - - 5 4 86 - 13 5 - - - - - - - - - - S80 STHRSPRS FLAKKLQ 1 34 34 - - - - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14 GRGAATMS LGKLSPV 0.13 - - - - - - - - 0.13 - S19 TMSLGKLS PVGWVSS -1.1e-15 - -0.038 - - -0.2 -7.8e-6 -0.66 -0.004 -1.9e-17 - S25 LSPVGWVS SSQGKRR -4e-17 - - - - - -1.3e-14 -2.7e-5 - - - S26 SPVGWVSS SQGKRRL - - - - - - - - - - - S27 PVGWVSSS QGKRRLT -0.1 - - - - - - - - -0.42 -0.13 T34 SQGKRRLT ADMISHP -3.7e-6 - -0.12 -3.8e-4 - -1.4e-8 -1.9e-7 - - 1.6e-8 - S71 LSNHGGSS GSTHRSP - - - - - - - - - - - S73 NHGGSSGS THRSPRS - - - - - - - - - - - S77 SSGSTHRS PRSFLAK - - - - - - - - - - - S80 STHRSPRS FLAKKLQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S14
S19
S25
S26
S27
T34
S71
S73
S77
S80
S101
S106
S113
S121
Y130
S132
S139
S142
S143
T145
S147
S152
S153
S169
S180
S183
S190
S192
S195
S303
S350
S353
S365
T367
T377
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation CCRCC S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation COAD S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation GBM S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation HNSCC S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation LSCC S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation LUAD S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation OV S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation PDAC S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation UCEC S14 S19 S25 S26 S27 T34 S71 S73 S77 S80 S101 S106 S113 S121 Y130 S132 S139 S142 S143 T145 S147 S152 S153 S169 S180 S183 S190 S192 S195 S303 S350 S353 S365 T367 T377 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S14
S19
S25
S26
S27
T34
S71
S73
S77
S80
S101
S106
S113
S121
Y130
S132
S139
S142
S143
T145
S147
S152
S153
S169
S180
S183
S190
S192
S195
S303
S350
S353
S365
T367
T377
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S14
S19
S25
S26
S27
T34
S71
S73
S77
S80
S101
S106
S113
S121
Y130
S132
S139
S142
S143
T145
S147
S152
S153
S169
S180
S183
S190
S192
S195
S303
S350
S353
S365
T367
T377
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.