MAST1: microtubule associated serine/threonine kinase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2m9x chain A
3ps4 chain A
3ps4 chain B
3ps4 chain C
3ps4 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T42 KSLILTST SPTLPRP 1 9 - - - - - - 9 - - - - - - - - - - - - - S43 SLILTSTS PTLPRPH 1 63 - - - - - - 63 - - - - - - - - - - - - - S51 PTLPRPHS PLPGHLG 1 9 - - - - - - 9 - - - - - - - - - - - - - S90 RADGRRWS LASLPSS 2 108 - - - - - - 99 - - - 5 4 - - - - - - - - S111 PSSTVSSS CSSQERL 1 45 - - - - - - 45 - - - - - - - - - - - - - S114 TVSSSCSS QERLHQL 1 18 - - - - - - 18 - - - - - - - - - - - - - S139 FLSKHFGS TESITDE 2 108 - - - - - - 99 - - - - - - - 7 2 - - - - T140 LSKHFGST ESITDED 1 18 - - - - - - 18 - - - - - - - - - - - - - S152 DEDGGRRS PAVRPRS 1 27 - - - - - - - - - - - - - - 22 5 - - - - S159 SPAVRPRS RSLSPGR 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T42 KSLILTST SPTLPRP - - - - - - - - - - - S43 SLILTSTS PTLPRPH - - - - - - - - - - - S51 PTLPRPHS PLPGHLG - - - - - - - - - - - S90 RADGRRWS LASLPSS - - - - - - - - - - - S111 PSSTVSSS CSSQERL - - - - - - - - - - - S114 TVSSSCSS QERLHQL - - - - - - - - - - - S139 FLSKHFGS TESITDE - - - - - - - - - - - T140 LSKHFGST ESITDED - - - - - - - - - - - S152 DEDGGRRS PAVRPRS - - - - - - - - - - - S159 SPAVRPRS RSLSPGR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T42
S43
S51
S90
S111
S114
S139
T140
S152
S159
S161
S163
S346
S349
T351
S668
S687
Y688
S717
S770
S779
S789
S799
S827
S893
S948
S951
S952
S966
S1120
S1127
T1129
S1136
S1217
S1242
S1310
S1362
S1413
S1424
S1425
S1426
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation CCRCC T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation COAD T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation GBM T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation HNSCC T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation LSCC T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation LUAD T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation OV T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation PDAC T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation UCEC T42 S43 S51 S90 S111 S114 S139 T140 S152 S159 S161 S163 S346 S349 T351 S668 S687 Y688 S717 S770 S779 S789 S799 S827 S893 S948 S951 S952 S966 S1120 S1127 T1129 S1136 S1217 S1242 S1310 S1362 S1413 S1424 S1425 S1426 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T42
S43
S51
S90
S111
S114
S139
T140
S152
S159
S161
S163
S346
S349
T351
S668
S687
Y688
S717
S770
S779
S789
S799
S827
S893
S948
S951
S952
S966
S1120
S1127
T1129
S1136
S1217
S1242
S1310
S1362
S1413
S1424
S1425
S1426
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T42
S43
S51
S90
S111
S114
S139
T140
S152
S159
S161
S163
S346
S349
T351
S668
S687
Y688
S717
S770
S779
S789
S799
S827
S893
S948
S951
S952
S966
S1120
S1127
T1129
S1136
S1217
S1242
S1310
S1362
S1413
S1424
S1425
S1426
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.