Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3tnu chain B
6jfv chain B
6jfv chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S2 ______MS RQSSVSF 1 72 - - - - - - - - 46 26 - - - - - - - - - - S5 ___MSRQS SVSFRSG 4 306 - - - - - - - - 76 44 80 68 - - 21 5 - - 12 - S6 __MSRQSS VSFRSGG 4 120 - - - - - - 9 - - - - - - - 34 8 4 2 50 13 S8 MSRQSSVS FRSGGSR 1 28 - - - - - - - - - - 15 13 - - - - - - - - S11 QSSVSFRS GGSRSFS 3 175 - - - - - - - - 67 39 34 29 - - - - - - 6 - S14 VSFRSGGS RSFSTAS 4 125 9 - - - - - - - 55 33 10 9 - - 8 1 - - - - S16 FRSGGSRS FSTASAI 9 837 88 - - - 7 2 9 - 108 62 103 92 28 24 66 17 90 37 87 17 S18 SGGSRSFS TASAITP 8 407 9 - - - - - 9 - 40 23 20 13 17 17 54 11 69 30 77 18 T19 GGSRSFST ASAITPS 7 255 65 - - - - - - - 64 37 20 16 8 9 5 3 16 6 6 - S21 SRSFSTAS AITPSVS 7 444 24 - - - - - - - 69 39 40 25 5 4 66 16 62 25 56 13
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S2 ______MS RQSSVSF -0.39 - - - - -0.39 - - - - - S5 ___MSRQS SVSFRSG 2.2e-11 - - - - 0.87 1.4e-20 - - - - S6 __MSRQSS VSFRSGG 0.023 - - - - - - - - - 0.023 S8 MSRQSSVS FRSGGSR - - - - - - - - - - - S11 QSSVSFRS GGSRSFS 2.5e-7 - - - - 5.0e-4 1.4e-4 - - - - S14 VSFRSGGS RSFSTAS -0.4 - - - - -0.4 - - - - - S16 FRSGGSRS FSTASAI 2.2e-6 - - - - 2.5e-5 2.9e-13 -0.024 -0.02 0.013 0.029 S18 SGGSRSFS TASAITP 0.22 - - - - -0.4 1.9e-3 - -0.005 0.083 0.12 T19 GGSRSFST ASAITPS 3.3e-7 - - - - 4.1e-3 1.4e-5 - - - - S21 SRSFSTAS AITPSVS 6.4e-5 - - - - 0.38 5.3e-9 - -0.091 8.3e-3 0.2
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S2
S5
S6
S8
S11
S14
S16
S18
T19
S21
T24
S26
S28
T30
S31
T33
S34
S36
S38
S50
Y60
S62
S64
Y66
S71
S75
S77
T78
S79
S82
S242
T267
S353
T355
S359
Y365
T371
S387
S567
S571
S572
S573
S574
S579
T580
T581
S582
S583
S584
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation CCRCC S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation COAD S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation GBM S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation HNSCC S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation LSCC S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation LUAD S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation OV S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation PDAC S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation UCEC S2 S5 S6 S8 S11 S14 S16 S18 T19 S21 T24 S26 S28 T30 S31 T33 S34 S36 S38 S50 Y60 S62 S64 Y66 S71 S75 S77 T78 S79 S82 S242 T267 S353 T355 S359 Y365 T371 S387 S567 S571 S572 S573 S574 S579 T580 T581 S582 S583 S584 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S2
S5
S6
S8
S11
S14
S16
S18
T19
S21
T24
S26
S28
T30
S31
T33
S34
S36
S38
S50
Y60
S62
S64
Y66
S71
S75
S77
T78
S79
S82
S242
T267
S353
T355
S359
Y365
T371
S387
S567
S571
S572
S573
S574
S579
T580
T581
S582
S583
S584
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S2
S5
S6
S8
S11
S14
S16
S18
T19
S21
T24
S26
S28
T30
S31
T33
S34
S36
S38
S50
Y60
S62
S64
Y66
S71
S75
S77
T78
S79
S82
S242
T267
S353
T355
S359
Y365
T371
S387
S567
S571
S572
S573
S574
S579
T580
T581
S582
S583
S584
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.