Protein: ENSP00000253107

PPAN:: peter pan homolog

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S443	FPKTKDKSQGAQARR	1	18	-	-	-	-	11	7	-	-	-	-	-	-	-	-	-	-	-	-	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S443	FPKTKDKSQGAQARR	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 1 of 1 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
HALLMARK_KRAS_SIGNALING_DN	S443	5.2e-3	-	-	5.2e-3	-	-	-	-	-	-	-
HALLMARK_MYC_TARGETS_V2	S443	0.012	-	-	0.012	-	-	-	-	-	-	-
xcell: Endothelial cell	S443	0.028	-	-	0.028	-	-	-	-	-	-	-
xcell: B cell naive	S443	0.03	-	-	0.03	-	-	-	-	-	-	-
cibersort: Myeloid dendritic cell activated	S443	0.12	-	-	0.12	-	-	-	-	-	-	-
HALLMARK_MTORC1_SIGNALING	S443	0.12	-	-	0.12	-	-	-	-	-	-	-
cibersort: Neutrophil	S443	0.14	-	-	0.14	-	-	-	-	-	-	-
xcell: Hematopoietic stem cell	S443	0.15	-	-	0.15	-	-	-	-	-	-	-
cibersort: Macrophage M2	S443	0.18	-	-	0.18	-	-	-	-	-	-	-
xcell: Monocyte	S443	0.19	-	-	0.19	-	-	-	-	-	-	-

Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
RIOK3	S443	0.04	-	-	0.04	-	-	-	-	-	-	-
TRIO	S443	0.044	-	-	0.044	-	-	-	-	-	-	-
SPEG	S443	0.048	-	-	0.048	-	-	-	-	-	-	-
CDK4	S443	0.052	-	-	0.052	-	-	-	-	-	-	-
TRIM33	S443	0.056	-	-	0.056	-	-	-	-	-	-	-
STK38L	S443	0.056	-	-	0.056	-	-	-	-	-	-	-
BAZ1A	S443	0.061	-	-	0.061	-	-	-	-	-	-	-
TAOK1	S443	0.076	-	-	0.076	-	-	-	-	-	-	-
MARK3	S443	0.087	-	-	0.087	-	-	-	-	-	-	-
MAP2K4	S443	0.094	-	-	0.094	-	-	-	-	-	-	-

Showing 1 to 10 of 538 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
INPP4A	S443	-0.023	-	-	-0.023	-	-	-	-	-	-	-
FBP1	S443	-0.087	-	-	-0.087	-	-	-	-	-	-	-
PPP2CB	S443	-0.094	-	-	-0.094	-	-	-	-	-	-	-
PTPRA	S443	-0.1	-	-	-0.1	-	-	-	-	-	-	-
MTMR14	S443	-0.1	-	-	-0.1	-	-	-	-	-	-	-
PPP3CA	S443	-0.13	-	-	-0.13	-	-	-	-	-	-	-
CTDP1	S443	-0.15	-	-	-0.15	-	-	-	-	-	-	-
SGPP1	S443	-0.15	-	-	-0.15	-	-	-	-	-	-	-
INPP5K	S443	-0.18	-	-	-0.18	-	-	-	-	-	-	-
PPP1CA	S443	-0.19	-	-	-0.19	-	-	-	-	-	-	-

Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000253107Gene: PPAN

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000253107
Gene: PPAN