RBSN: rabenosyn, RAB effector
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1yzm chain A
1z0j chain B
1z0k chain B
1z0k chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S209 LTSASKES LSTHTSP 1 8 - - - - - - - - - - - - - - 7 1 - - - - S211 SASKESLS THTSPSQ 1 18 - - - - - - 18 - - - - - - - - - - - - - T214 KESLSTHT SPSQSPN 1 18 - - - - - - 18 - - - - - - - - - - - - - S215 ESLSTHTS PSQSPNS 6 182 18 - - - 6 11 82 - 5 3 - - 4 4 40 9 - - - - S217 LSTHTSPS QSPNSVH 4 58 - - - - 6 11 25 - 5 3 - - 4 4 - - - - - - S219 THTSPSQS PNSVHGS 3 89 - - - - 5 4 53 - - - - - - - 22 5 - - - - S222 SPSQSPNS VHGSRRG 1 9 - - - - - - 9 - - - - - - - - - - - - - S226 SPNSVHGS RRGSISS 3 104 - - - - 5 4 45 - - - - - - - 43 7 - - - - S230 VHGSRRGS ISSMSSV 10 1301 104 - 63 41 42 48 99 - 102 59 108 99 106 97 61 16 105 44 89 18 S232 GSRRGSIS SMSSVSS 8 87 - - 7 7 10 8 9 - 6 3 - - 8 8 7 1 4 1 6 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S209 LTSASKES LSTHTSP - - - - - - - - - - - S211 SASKESLS THTSPSQ - - - - - - - - - - - T214 KESLSTHT SPSQSPN - - - - - - - - - - - S215 ESLSTHTS PSQSPNS - - - - - - - - - - - S217 LSTHTSPS QSPNSVH - - - - - - - - - - - S219 THTSPSQS PNSVHGS - - - - - - - - - - - S222 SPSQSPNS VHGSRRG - - - - - - - - - - - S226 SPNSVHGS RRGSISS - - - - - - - - - - - S230 VHGSRRGS ISSMSSV -6.8e-56 - -0.004 -6.1e-9 - -3.5e-19 -3.2e-17 -1.2e-7 -0.6 -2.5e-12 -1.7e-8 S232 GSRRGSIS SMSSVSS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S209
S211
T214
S215
S217
S219
S222
S226
S230
S232
S233
S235
S236
S238
S239
S429
S541
S548
S577
S578
T588
S590
S601
S635
T642
S684
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation CCRCC S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation COAD S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation GBM S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation HNSCC S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation LSCC S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation LUAD S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation OV S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation PDAC S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation UCEC S209 S211 T214 S215 S217 S219 S222 S226 S230 S232 S233 S235 S236 S238 S239 S429 S541 S548 S577 S578 T588 S590 S601 S635 T642 S684 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S209
S211
T214
S215
S217
S219
S222
S226
S230
S232
S233
S235
S236
S238
S239
S429
S541
S548
S577
S578
T588
S590
S601
S635
T642
S684
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S209
S211
T214
S215
S217
S219
S222
S226
S230
S232
S233
S235
S236
S238
S239
S429
S541
S548
S577
S578
T588
S590
S601
S635
T642
S684
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.