Protein: ENSP00000253754
Gene: PDLIM4

LinkedOmicsKB © 2022-2023 Zhang Lab

PDLIM4:
PDZ and LIM domain 4

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S4____MPHSVTLRGPS3150----21249-----------7818
S11SVTLRGPSPWGFRLV101020105-1111575999-10862857754751895369518
S81DHLTLSVSRPEGRSW235------9---1412--------
S87VSRPEGRSWPSAPDD822116-44--27-541091412--648818
S112DPEIQDGSPTTSRRP101535122-103809710099-1025910899105978319105449518
T114EIQDGSPTTSRRPSG16------------------6-
S116QDGSPTTSRRPSGTG4185----4752----108--72--527
S120PTTSRRPSGTGTGPE10126886-45339710099-10159847568618318105449218
T122TSRRPSGTGTGPEDG66018-4445----5554----6-
T124RRPSGTGTGPEDGRP6729-441215------45--41113
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S4____MPHSVTLRGPS-0.12---5.3e-3------0.56
S11SVTLRGPSPWGFRLV1.8e-4---5.4e-10-0.0154.3e-16--0.811.5e-10-0.18
S81DHLTLSVSRPEGRSW-----------
S87VSRPEGRSWPSAPDD0.68---------0.68
S112DPEIQDGSPTTSRRP4.9e-5--6.5e-3-1.8e-11-0.132.9e-181.8e-10-0.0283e-90.55
T114EIQDGSPTTSRRPSG-----------
S116QDGSPTTSRRPSGTG-0.017---0.017-------
S120PTTSRRPSGTGTGPE1.9e-3--0.43-1.4e-8-0.153e-122.1e-5-0.0041.8e-60.51
T122TSRRPSGTGTGPEDG-----------
T124RRPSGTGTGPEDGRP-----------
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationCCRCCS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationCOADS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationGBMS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationHNSCCS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationLSCCS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationLUADS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationOVS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationPDACS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylationUCECS4S11S81S87S112T114S116S120T122T124S132S135S150T154T161S165S188S240S247T265proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.