Protein: ENSP00000254480
Gene: SMARCC1

LinkedOmicsKB © 2022-2023 Zhang Lab

SMARCC1:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y236VLVHWGFYPDSYDTW177-------------------
S310KNEEPVRSPERRDRK101552122-103809710099-10862108991101018318105449518
S328NARKRKHSPSPPPPT1071024-44818089-73414539272225756245316
S330RKRKHSPSPPPPTPT10832113-1616353645-34209387847761151486513
T335SPSPPPPTPTESRKK91296114-9176908999-5832108999886--105448918
S350SGKKGQASLYGKRRS6219--87----5130--542151045618
S357SLYGKRRSQKEEDEQ3190----6055--------439--1211
T368EDEQEDLTKDMEDPT254----------1010------286
T375TKDMEDPTPVPNIEE619312-------7334321816--32597
T398LKKDSENTPVKGGTV1083777-7812662-331998779885671551218318
Showing 1 to 10 of 22 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y236VLVHWGFYPDSYDTW-----------
S310KNEEPVRSPERRDRK1.5e-22--2.2e-257.4e-25-1.1e-62.7e-315e-302.2e-3-1.2e-100.29
S328NARKRKHSPSPPPPT4.2e-22--4.9e-8-0.153e-151.3e-4-1.0e-40.24
S330RKRKHSPSPPPPTPT9e-10--0.055--0.882.2e-155.9e-50.13--0.81
T335SPSPPPPTPTESRKK2.6e-51--5.0e-51.4e-15-5.9e-72e-317.1e-25-4.6e-44.4e-8
S350SGKKGQASLYGKRRS8.9e-6----2.2e-6----0.12
S357SLYGKRRSQKEEDEQ5.9e-5--5.9e-5-------
T368EDEQEDLTKDMEDPT-----------
T375TKDMEDPTPVPNIEE5.4e-6-----5.4e-6----
T398LKKDSENTPVKGGTV1.3e-37----5.8e-31.8e-292.1e-282.5e-30.0320.25
Showing 1 to 10 of 22 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationCCRCCY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationCOADY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationGBMY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationHNSCCY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationLSCCY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationLUADY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationOVY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationPDACY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylationUCECY236S310S328S330T335S350S357T368T375T398T404S434S573S748T801S816S822S825T828S830T842S862proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.