Protein: ENSP00000257118
Gene: PHC2

LinkedOmicsKB © 2022-2023 Zhang Lab

PHC2:
polyhomeotic homolog 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S155QLLNRAQSVNSAAAS116------------------115
S182SSPALTASQAQMYLR228------19------------9
T218GSPARPPTPAQVQNL121------21-------------
S275SRNTAQASPAGAKPG7311--44--72-64646043--1345716
T618PQQDHTTTTDSEMEE84328-1916--89-5234335852--3717557
T619QQDHTTTTDSEMEEP1033818-211910864-117302798438135325
S621DHTTTTDSEMEEPYL1054457-373310871-462663582120248155375
S682KRVGLFHSDRSKLQK223--86------54--------
S685GLFHSDRSKLQKAGA132----------------2210--
S701THNRRRASKASLPPL732751-291299----20187065--931814
Showing 1 to 10 of 15 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S155QLLNRAQSVNSAAAS-----------
S182SSPALTASQAQMYLR-----------
T218GSPARPPTPAQVQNL-----------
S275SRNTAQASPAGAKPG-3.3e-6------0.16----2.2e-7
T618PQQDHTTTTDSEMEE-4.9e-3------1.6e-60.94--0.88-
T619QQDHTTTTDSEMEEP0.25-3.6e-6----2.7e-3----
S621DHTTTTDSEMEEPYL0.75-1.0e-4--0.86-4.5e-4-0.24---
S682KRVGLFHSDRSKLQK-----------
S685GLFHSDRSKLQKAGA0.95--------0.95-
S701THNRRRASKASLPPL0.93-1e-9----0.077-7.1e-6---
Showing 1 to 10 of 15 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationCCRCCS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationCOADS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationGBMS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationHNSCCS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationLSCCS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationLUADS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationOVS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationPDACS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylationUCECS155S182T218S275T618T619S621S682S685S701S704T731S733S751S754proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.