Protein: ENSP00000258416
Gene: EIF4E2

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF4E2:
eukaryotic translation initiation factor 4E family member 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S13DALKDDDSGDHDQNE8616--2515--99-41215045272435594397818
S23HDQNEENSTQKDGEK233----------108------132
T68TFWYSRRTPGRPTSS577--33----1151091312--83--
S74RTPGRPTSSQSYEQN3156--2521--------3633--2912--
S75TPGRPTSSQSYEQNI3202--1211----7443------4319--
S77GRPTSSQSYEQNIKQ7317--98--9-9656541212--702772
Y78RPTSSQSYEQNIKQI220--122------------42--
Showing 1 to 7 of 7 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S13DALKDDDSGDHDQNE7.3e-4--0.35--0.0141.1e-53.2e-9--2.6e-3-0.58
S23HDQNEENSTQKDGEK-----------
T68TFWYSRRTPGRPTSS-----------
S74RTPGRPTSSQSYEQN-1.3e-5-2.3e-5-----3.8e-20--9.8e-3-
S75TPGRPTSSQSYEQNI-2.8e-4-----2.6e-3----0.033-
S77GRPTSSQSYEQNIKQ2.2e-5----1.6e-11----0.46-
Y78RPTSSQSYEQNIKQI-----------
Showing 1 to 7 of 7 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS13S23T68S74S75S77Y78proteinRNASCNVmethylationCCRCCS13S23T68S74S75S77Y78proteinRNASCNVmethylationCOADS13S23T68S74S75S77Y78proteinRNASCNVmethylationGBMS13S23T68S74S75S77Y78proteinRNASCNVmethylationHNSCCS13S23T68S74S75S77Y78proteinRNASCNVmethylationLSCCS13S23T68S74S75S77Y78proteinRNASCNVmethylationLUADS13S23T68S74S75S77Y78proteinRNASCNVmethylationOVS13S23T68S74S75S77Y78proteinRNASCNVmethylationPDACS13S23T68S74S75S77Y78proteinRNASCNVmethylationUCECS13S23T68S74S75S77Y78proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.