NMT1:
N-myristoyltransferase 1

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S47SYNRGGLSPANDTGA101453122-62489710099-1025910899100938319105449518
S69KKKKEKGSETDSAQD258------27-----------1813
T71KKEKGSETDSAQDQP4326---------544472----
S73EKGSETDSAQDQPVK101258104-7765566073-1035893851059726797399518
S83DQPVKMNSLPAERIQ10830104-6845221418-281610899424149950227718
S116MEEASKRSYQFWDTQ4849-44--------1411----375
Y327MQRTMKLYRLPETPK636139-2812------30274440--6929403
T332KLYRLPETPKTAGLR636139-2812------30274440--6929403
Showing 1 to 8 of 8 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S47SYNRGGLSPANDTGA8.8e-52-1.6e-152.2e-29-5.8e-112.3e-301.1e-15-0.25-8.2e-111.8e-7
S69KKKKEKGSETDSAQD-----------
T71KKEKGSETDSAQDQP-----------
S73EKGSETDSAQDQPVK1.3e-50-5.1e-79.4e-10-3.1e-101e-272.1e-27--9.2e-42.1e-4
S83DQPVKMNSLPAERIQ0.31-8.9e-130.81-2.3e-4-3.9e-90.38--5.1e-50.49
S116MEEASKRSYQFWDTQ-----------
Y327MQRTMKLYRLPETPK2.8e-10--0.74---2.1e-114e-9-0.71-
T332KLYRLPETPKTAGLR2.8e-10--0.74---2.1e-114e-9-0.71-
Showing 1 to 8 of 8 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationCCRCCS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationCOADS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationGBMS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationHNSCCS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationLSCCS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationLUADS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationOVS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationPDACS47S69T71S73S83S116Y327T332proteinRNASCNVmethylationUCECS47S69T71S73S83S116Y327T332proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.