Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2kpw chain A
3jt0 chain A
3jt0 chain B
3tyy chain A
3tyy chain B
3umn chain A
3umn chain B
3umn chain C
5vvx chain B
5vvx chain D
7dtg chain A
7dtg chain B
7dtg chain C
7dtg chain D
7dtg chain E
7dtg chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T20 SRAGGPTT PLSPTRL 10 1199 96 - 82 60 97 100 80 - 73 39 78 72 66 60 83 19 68 26 91 9 S23 GGPTTPLS PTRLSRL 10 1229 108 - 82 68 97 100 63 - 103 59 73 67 96 89 46 12 68 31 54 13 S28 PLSPTRLS RLQEKEE 7 163 15 - 4 4 - - 9 - - - 15 14 8 7 20 6 - - 46 15 S52 VYIDKVRS LETENSA 2 19 - - - - - - - - 6 3 5 5 - - - - - - - - S58 RSLETENS ALQLQVT 3 24 7 - - - - - - - - - - - - - 7 2 - - 8 - S126 LNYAKKES DLNGAQI 7 351 48 - 20 12 - - 9 - - - 9 8 74 70 - - 45 18 24 14 S158 TALGDKKS LEGDLED 8 516 40 - 37 27 - - 54 - 11 7 60 54 48 45 - - 31 13 71 18 S200 DLENRCQS LTEDLEF 9 508 17 - - - 14 13 45 - 63 37 24 23 14 12 21 5 92 39 71 18 S210 EDLEFRKS MYEEEIN 5 139 - - - - - - - - 50 31 15 14 - - 8 1 3 2 6 9 S232 TRLVEVDS GRQIEYE 10 864 81 - 57 45 18 26 26 - 49 31 69 64 101 92 35 7 90 37 23 13
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T20 SRAGGPTT PLSPTRL 6.5e-17 - 2.3e-7 8e-22 - -0.04 0.048 0.65 0.055 4.4e-7 - S23 GGPTTPLS PTRLSRL 1e-21 - 4.2e-12 3.3e-26 - 0.55 -0.12 1.2e-5 -0.12 4.5e-10 0.15 S28 PLSPTRLS RLQEKEE -0.91 - - - - - - - - - -0.91 S52 VYIDKVRS LETENSA - - - - - - - - - - - S58 RSLETENS ALQLQVT - - - - - - - - - - - S126 LNYAKKES DLNGAQI -9.5e-17 - -7.4e-5 - - - - -3.9e-4 - -2.7e-10 -5.1e-3 S158 TALGDKKS LEGDLED 5.9e-8 - 0.73 - - - 6.7e-8 6.5e-11 - -0.26 0.33 S200 DLENRCQS LTEDLEF 4.2e-21 - - - - 3.3e-4 2.4e-12 - - 1.4e-11 0.14 S210 EDLEFRKS MYEEEIN 8.1e-5 - - - - 8.1e-5 - - - - - S232 TRLVEVDS GRQIEYE 3e-49 - 5.5e-16 - - 6.9e-3 5.8e-17 6.7e-17 - 6.7e-8 1.3e-3
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T20
S23
S28
S52
S58
S126
S158
S200
S210
S232
S278
S279
T283
S284
S288
S302
S305
S308
S375
S401
S404
S405
S406
S408
S520
T523
S534
S543
T549
T575
S579
S582
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation CCRCC T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation COAD T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation GBM T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation HNSCC T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation LSCC T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation LUAD T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation OV T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation PDAC T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation UCEC T20 S23 S28 S52 S58 S126 S158 S200 S210 S232 S278 S279 T283 S284 S288 S302 S305 S308 S375 S401 S404 S405 S406 S408 S520 T523 S534 S543 T549 T575 S579 S582 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T20
S23
S28
S52
S58
S126
S158
S200
S210
S232
S278
S279
T283
S284
S288
S302
S305
S308
S375
S401
S404
S405
S406
S408
S520
T523
S534
S543
T549
T575
S579
S582
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T20
S23
S28
S52
S58
S126
S158
S200
S210
S232
S278
S279
T283
S284
S288
S302
S305
S308
S375
S401
S404
S405
S406
S408
S520
T523
S534
S543
T549
T575
S579
S582
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.