SPECC1: sperm antigen with calponin homology and coiled-coil domains 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S37 SGMKSSKS STSLAFE 7 470 9 - - - - - 99 - - - 55 49 13 11 21 5 70 32 88 18 S54 LSRLKRAS SEDTLNK 6 258 9 - 9 7 - - 9 - - - 58 57 48 45 - - 11 5 - - S55 SRLKRASS EDTLNKP 10 1354 71 - 63 51 79 82 99 - 108 62 98 90 102 93 76 18 105 44 95 18 T58 KRASSEDT LNKPGST 1 16 - - 8 8 - - - - - - - - - - - - - - - - T78 VRLKKTAT AGAISEL 9 526 50 - 10 8 - - 99 - 12 7 64 57 34 31 8 1 50 21 65 9 S120 VTVSRERS VPRGPSN 6 282 57 - 8 7 - - - - 25 11 30 29 - - - - 54 22 28 11 S131 GPSNPRKS VSSPTSS 10 891 37 - 8 8 67 67 91 - 64 38 70 63 26 24 63 14 105 42 95 9 S134 NPRKSVSS PTSSNTP 9 306 6 - - - 28 26 90 - 18 10 5 5 4 4 36 6 9 4 51 4 T136 RKSVSSPT SSNTPTP 7 105 - - 4 4 - - - - 5 4 5 5 13 12 6 2 27 12 6 - S138 SVSSPTSS NTPTPTK 1 6 - - - - - - - - - - - - - - - - 4 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S37 SGMKSSKS STSLAFE 0.024 - - - - - 0.01 - - 4.6e-6 -1.2e-3 S54 LSRLKRAS SEDTLNK -1.5e-29 - - - - - -7.8e-16 -2.6e-15 - - - S55 SRLKRASS EDTLNKP -6.6e-4 - 1.8e-7 -0.094 - -0.25 -3.5e-15 -3.4e-9 -0.78 7.6e-8 -8.7e-4 T58 KRASSEDT LNKPGST - - - - - - - - - - - T78 VRLKKTAT AGAISEL -0.93 - - - - - 0.22 -2.4e-3 - 0.05 - S120 VTVSRERS VPRGPSN 0.28 - - - - 2.5e-3 -0.29 - - 0.71 -0.87 S131 GPSNPRKS VSSPTSS 0.013 - - -0.26 - 0.065 -9.7e-6 0.4 0.074 7.7e-13 - S134 NPRKSVSS PTSSNTP -8.9e-3 - - -8.9e-3 - - - - - - - T136 RKSVSSPT SSNTPTP 0.71 - - - - - - - - 0.71 - S138 SVSSPTSS NTPTPTK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S37
S54
S55
T58
T78
S120
S131
S134
T136
S138
T140
T142
T149
S151
T199
T215
S216
S218
S241
T311
S312
S314
S315
S316
S317
S325
S329
S344
S345
T346
S347
S360
S361
S364
S366
S369
S372
T424
S425
S553
S617
S654
T809
S810
T812
S826
S840
S847
S863
S878
S912
S914
S917
S919
S923
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation CCRCC S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation COAD S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation GBM S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation HNSCC S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation LSCC S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation LUAD S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation OV S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation PDAC S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation UCEC S37 S54 S55 T58 T78 S120 S131 S134 T136 S138 T140 T142 T149 S151 T199 T215 S216 S218 S241 T311 S312 S314 S315 S316 S317 S325 S329 S344 S345 T346 S347 S360 S361 S364 S366 S369 S372 T424 S425 S553 S617 S654 T809 S810 T812 S826 S840 S847 S863 S878 S912 S914 S917 S919 S923 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S37
S54
S55
T58
T78
S120
S131
S134
T136
S138
T140
T142
T149
S151
T199
T215
S216
S218
S241
T311
S312
S314
S315
S316
S317
S325
S329
S344
S345
T346
S347
S360
S361
S364
S366
S369
S372
T424
S425
S553
S617
S654
T809
S810
T812
S826
S840
S847
S863
S878
S912
S914
S917
S919
S923
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S37
S54
S55
T58
T78
S120
S131
S134
T136
S138
T140
T142
T149
S151
T199
T215
S216
S218
S241
T311
S312
S314
S315
S316
S317
S325
S329
S344
S345
T346
S347
S360
S361
S364
S366
S369
S372
T424
S425
S553
S617
S654
T809
S810
T812
S826
S840
S847
S863
S878
S912
S914
S917
S919
S923
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.