Protein: ENSP00000261866
Gene: SPG11

LinkedOmicsKB © 2022-2023 Zhang Lab

SPG11:
SPG11 vesicle trafficking associated, spatacsin

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S1827PRFSRQISTSGELSF84139-1210--90-6839494537338193--
S1829FSRQISTSGELSFDS213--44------------32--
S1937EIHALLQSAELLEEE116--124----------------
S1955IPLRRVHSTSSLDSQ1056632-9810890-75442421403534861282514
T1956PLRRVHSTSSLDSQK71627-2514459---19182624--74--
S1957LRRVHSTSSLDSQKF829857-4481055---5545401433216--
S1958RRVHSTSSLDSQKFV105206-44294290-6336504512115314219292
S1961HSTSSLDSQKFVTVP5193----121580-54------3114239
S1969QKFVTVPSSNEVVTN110--------73----------
Showing 1 to 9 of 9 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S1827PRFSRQISTSGELSF-0.68----1.1e-3-4.8e-50.93---
S1829FSRQISTSGELSFDS-----------
S1937EIHALLQSAELLEEE-----------
S1955IPLRRVHSTSSLDSQ1.2e-7----1.1e-40.451.4e-6--0.880.012
T1956PLRRVHSTSSLDSQK0.83--0.19----0.11---
S1957LRRVHSTSSLDSQKF-0.5------0.27--0.04-
S1958RRVHSTSSLDSQKFV-4.7e-6---0.82--0.03-1.6e-7--0.13--
S1961HSTSSLDSQKFVTVP-0.054---------0.054-
S1969QKFVTVPSSNEVVTN-----------
Showing 1 to 9 of 9 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationCCRCCS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationCOADS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationGBMS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationHNSCCS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationLSCCS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationLUADS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationOVS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationPDACS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylationUCECS1827S1829S1937S1955T1956S1957S1958S1961S1969proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.