DAPK2: death associated protein kinase 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1wmk chain A
1wmk chain B
1wmk chain C
1wmk chain D
1wmk chain E
1wmk chain F
1wmk chain G
1wmk chain H
1wrz chain B
1z9x chain A
1z9x chain B
1z9x chain C
1zuz chain B
1zws chain A
1zws chain B
1zws chain C
1zws chain D
1zws chain E
1zws chain F
1zws chain G
1zws chain H
2a27 chain A
2a27 chain B
2a27 chain C
2a27 chain D
2a27 chain E
2a27 chain F
2a27 chain G
2a27 chain H
2a2a chain A
2a2a chain B
2a2a chain C
2a2a chain D
2cke chain A
2cke chain B
2cke chain C
2cke chain D
6paw chain A
6paw chain B
6paw chain E
6paw chain F
7a6r chain E
7a6r chain F
7a6r chain G
7a6r chain L
7a6y chain J
7a6y chain K
7a6y chain L
7a6y chain M
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T45 KKCREKST GLEYAAK 1 9 - - - - - - 9 - - - - - - - - - - - - - Y49 EKSTGLEY AAKFIKK 1 9 - - - - - - 9 - - - - - - - - - - - - - S299 QAMVRRES VVNLENF 10 1486 122 - 103 80 97 100 62 - 108 62 108 99 110 101 83 19 97 41 76 18 S349 EDLRNCES DTEEDIA 10 980 97 - 27 25 81 80 36 - 62 38 79 72 58 52 41 10 94 38 72 18 T351 LRNCESDT EEDIARR 1 19 - - - - - - - - 13 6 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T45 KKCREKST GLEYAAK - - - - - - - - - - - Y49 EKSTGLEY AAKFIKK - - - - - - - - - - - S299 QAMVRRES VVNLENF -6.1e-28 - -1.5e-20 0.11 - 5.2e-3 -3.7e-34 -1.3e-30 -0.67 0.27 -1.9e-3 S349 EDLRNCES DTEEDIA -0.048 - -0.61 2.0e-4 - 0.79 -3.3e-13 -5.4e-5 -0.012 4.2e-7 -0.75 T351 LRNCESDT EEDIARR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T45
Y49
S299
S349
T351
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T45 Y49 S299 S349 T351 protein RNA SCNV methylation CCRCC T45 Y49 S299 S349 T351 protein RNA SCNV methylation COAD T45 Y49 S299 S349 T351 protein RNA SCNV methylation GBM T45 Y49 S299 S349 T351 protein RNA SCNV methylation HNSCC T45 Y49 S299 S349 T351 protein RNA SCNV methylation LSCC T45 Y49 S299 S349 T351 protein RNA SCNV methylation LUAD T45 Y49 S299 S349 T351 protein RNA SCNV methylation OV T45 Y49 S299 S349 T351 protein RNA SCNV methylation PDAC T45 Y49 S299 S349 T351 protein RNA SCNV methylation UCEC T45 Y49 S299 S349 T351 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T45
Y49
S299
S349
T351
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T45
Y49
S299
S349
T351
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.