Protein: ENSP00000262033
Gene: PTGES3

LinkedOmicsKB © 2022-2023 Zhang Lab

PTGES3:
prostaglandin E synthase 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S39EKSKLTFSCLGGSDN831917-17166326-7363571716----647
S44TFSCLGGSDNFKHLN101239114-9170555299-9857837796887197419518
S64HCIDPNDSKHKRTDR4131--88--54---15141715------
S72KHKRTDRSILCCLRK5157------35---20171312--92427
S82CCLRKGESGQSWPRL375----4553-----------13-
S85RKGESGQSWPRLTKE101263107-9068828845-91541089911010121595394416
T90GQSWPRLTKERAKLN216----------55------6-
S100RAKLNWLSVDFNNWK75729-8370--90-583329258477--95--
S113WKDWEDDSDEDMSNF101553122-103809710099-10862108991101018319105449518
S118DDSDEDMSNFDRFSE84447-1410465219---3532938538832--
Showing 1 to 10 of 13 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S39EKSKLTFSCLGGSDN7.4e-3-----7.4e-3----
S44TFSCLGGSDNFKHLN0.65--0.002-0.46--0.37-0.52-0.041-6.8e-60.088
S64HCIDPNDSKHKRTDR-----------
S72KHKRTDRSILCCLRK0.6-----0.6----
S82CCLRKGESGQSWPRL-----------
S85RKGESGQSWPRLTKE6.7e-22--8.4e-121.8e-22-2.1e-74.7e-147.7e-4-0.481e-8
T90GQSWPRLTKERAKLN-----------
S100RAKLNWLSVDFNNWK-3.8e-3--0.74---1.1e-4-0.0150.4---
S113WKDWEDDSDEDMSNF4.1e-12--0.762.6e-3-0.0178.2e-103.4e-10-0.610.890.013
S118DDSDEDMSNFDRFSE7.3e-8--0.22---0.469.2e-19---
Showing 1 to 10 of 13 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationCCRCCS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationCOADS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationGBMS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationHNSCCS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationLSCCS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationLUADS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationOVS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationPDACS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylationUCECS39S44S64S72S82S85T90S100S113S118S124S148S151proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.