PHF3: PHD finger protein 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2dme chain A
6ic8 chain A
6ic8 chain B
6ic9 chain A
6ic9 chain B
6q2v chain A
6q2v chain B
6q2v chain C
6q2v chain D
6q2v chain E
6q2v chain F
6q2v chain G
6q2v chain H
6q5y chain A
6q5y chain B
6q5y chain C
6q5y chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T101 VKESGNDT IDEEELI 5 172 - - 20 4 - - - - 68 38 9 8 - - 8 1 - - 5 11 S125 VEENSVRS PRKSPRL 10 1496 113 - 103 80 85 94 99 - 108 62 108 99 106 97 75 18 100 42 89 18 S283 CKAKPVGS PLFKFSD 10 1503 122 - 103 80 97 100 99 - 103 60 103 95 96 89 76 18 105 44 95 18 S299 EEHEQNDS ISGKTGE 4 127 69 - - - - - - - 11 7 19 17 - - - - - - 4 - S341 HILEDAGS SDISSDA 6 62 8 - 4 4 - - - - 6 3 10 10 5 4 - - - - 5 3 S342 ILEDAGSS DISSDAA 7 190 6 - 7 7 - - 55 - 11 5 20 17 9 7 - - - - 30 16 S345 DAGSSDIS SDAACTN 5 55 6 - - - - - 9 - - - 5 5 - - - - 4 2 21 3 S346 AGSSDISS DAACTNP 3 21 6 - - - - - 9 - - - - - - - - - 4 2 - - S359 NPNKTENS LVGLPSC 6 237 6 - 4 2 - - - - 6 4 69 64 40 36 - - - - 6 - T390 IADKTENT LERNKIE 1 9 - - - - - - - - - - 5 4 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T101 VKESGNDT IDEEELI 5.5e-11 - - - - 5.4e-11 - - - - - S125 VEENSVRS PRKSPRL 4.3e-32 - 2.8e-3 1.3e-7 - 5.1e-14 6.4e-27 1.4e-20 4.4e-4 -1.7e-11 0.46 S283 CKAKPVGS PLFKFSD -0.2 - -0.071 0.015 - -0.13 -0.025 0.93 6.4e-4 -0.83 -1.6e-4 S299 EEHEQNDS ISGKTGE - - - - - - - - - - - S341 HILEDAGS SDISSDA - - - - - - - - - - - S342 ILEDAGSS DISSDAA 1.5e-4 - - - - - 1.2e-4 - - - 0.13 S345 DAGSSDIS SDAACTN - - - - - - - - - - - S346 AGSSDISS DAACTNP - - - - - - - - - - - S359 NPNKTENS LVGLPSC 0.21 - - - - - 0.21 0.59 - - - T390 IADKTENT LERNKIE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T101
S125
S283
S299
S341
S342
S345
S346
S359
T390
S419
S477
T593
S595
S597
S677
S678
S680
S682
S702
S705
S707
T715
S752
S840
S868
S869
T1034
S1084
S1133
S1148
S1168
S1178
S1184
S1356
S1362
S1505
T1610
S1611
S1613
S1614
T1639
S1642
S1665
S1667
S1722
S1724
S1758
T1770
S1788
S1898
S1925
S1952
S1975
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation CCRCC T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation COAD T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation GBM T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation HNSCC T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation LSCC T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation LUAD T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation OV T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation PDAC T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation UCEC T101 S125 S283 S299 S341 S342 S345 S346 S359 T390 S419 S477 T593 S595 S597 S677 S678 S680 S682 S702 S705 S707 T715 S752 S840 S868 S869 T1034 S1084 S1133 S1148 S1168 S1178 S1184 S1356 S1362 S1505 T1610 S1611 S1613 S1614 T1639 S1642 S1665 S1667 S1722 S1724 S1758 T1770 S1788 S1898 S1925 S1952 S1975 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T101
S125
S283
S299
S341
S342
S345
S346
S359
T390
S419
S477
T593
S595
S597
S677
S678
S680
S682
S702
S705
S707
T715
S752
S840
S868
S869
T1034
S1084
S1133
S1148
S1168
S1178
S1184
S1356
S1362
S1505
T1610
S1611
S1613
S1614
T1639
S1642
S1665
S1667
S1722
S1724
S1758
T1770
S1788
S1898
S1925
S1952
S1975
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T101
S125
S283
S299
S341
S342
S345
S346
S359
T390
S419
S477
T593
S595
S597
S677
S678
S680
S682
S702
S705
S707
T715
S752
S840
S868
S869
T1034
S1084
S1133
S1148
S1168
S1178
S1184
S1356
S1362
S1505
T1610
S1611
S1613
S1614
T1639
S1642
S1665
S1667
S1722
S1724
S1758
T1770
S1788
S1898
S1925
S1952
S1975
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.