- PKMYT1:
- protein kinase, membrane associated tyrosine/threonine 1
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
T17 | MPMPTEGTPPPLSGT | 7 | 136 | 16 | - | 4 | 4 | - | - | - | - | 15 | 10 | 30 | 26 | 5 | 4 | 13 | - | - | - | 7 | 2 |
S50 | RPRGLSRSLPPPPPA | 1 | 9 | - | - | - | - | - | - | - | - | 6 | 3 | - | - | - | - | - | - | - | - | - | - |
S94 | EASETLQSPGYDPSR | 2 | 26 | - | - | - | - | - | - | - | - | - | - | 10 | 8 | 4 | 4 | - | - | - | - | - | - |
S120 | LSRLGHGSYGEVFKV | 1 | 6 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 6 | - |
Y121 | SRLGHGSYGEVFKVR | 1 | 10 | - | - | - | - | - | - | - | - | - | - | 5 | 5 | - | - | - | - | - | - | - | - |
S143 | YAVKRSMSPFRGPKD | 9 | 774 | 122 | - | 16 | 16 | 66 | 59 | 55 | - | 108 | 62 | 93 | 84 | 18 | 15 | - | - | 20 | 8 | 29 | 3 |
S160 | RKLAEVGSHEKVGQH | 1 | 8 | - | - | 4 | 4 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
T455 | RTVGSTSTPRSRCTP | 8 | 749 | 95 | - | - | - | 56 | 43 | 45 | - | 93 | 51 | 74 | 67 | 53 | 47 | - | - | 46 | 17 | 47 | 15 |
S473 | LDLSDINSEPPRGSF | 3 | 36 | 8 | - | - | - | - | - | - | - | - | - | 5 | 5 | 10 | 8 | - | - | - | - | - | - |
S479 | NSEPPRGSFPSFEPR | 4 | 94 | 6 | - | - | - | - | - | 46 | - | 6 | 4 | - | - | - | - | - | - | - | - | 25 | 7 |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
T17 | MPMPTEGTPPPLSGT | 0.011 | - | - | - | - | - | 0.011 | - | - | - | - |
S50 | RPRGLSRSLPPPPPA | - | - | - | - | - | - | - | - | - | - | - |
S94 | EASETLQSPGYDPSR | - | - | - | - | - | - | - | - | - | - | - |
S120 | LSRLGHGSYGEVFKV | - | - | - | - | - | - | - | - | - | - | - |
Y121 | SRLGHGSYGEVFKVR | - | - | - | - | - | - | - | - | - | - | - |
S143 | YAVKRSMSPFRGPKD | 1.9e-61 | - | - | 8e-14 | - | 1.8e-22 | 3.1e-30 | - | - | - | - |
S160 | RKLAEVGSHEKVGQH | - | - | - | - | - | - | - | - | - | - | - |
T455 | RTVGSTSTPRSRCTP | 4.9e-35 | - | - | 1.0e-5 | - | 3.3e-9 | 6.2e-24 | 6.7e-14 | - | 0.78 | 0.039 |
S473 | LDLSDINSEPPRGSF | - | - | - | - | - | - | - | - | - | - | - |
S479 | NSEPPRGSFPSFEPR | - | - | - | - | - | - | - | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |