RHBDF1: rhomboid 5 homolog 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S8 MSEARRDS TSSLQRK 10 343 24 - 16 8 15 12 27 - 16 10 15 14 18 15 62 14 24 9 35 9 T9 SEARRDST SSLQRKK 5 71 - - - - 14 13 9 - - - 10 9 - - - - 6 2 5 3 S10 EARRDSTS SLQRKKP 3 25 8 - 8 - 3 6 - - - - - - - - - - - - - - S11 ARRDSTSS LQRKKPP 7 210 21 - 24 21 5 4 45 - - - - - - - 44 7 5 1 29 4 S51 QAFLRSVS MPAETAH 6 310 41 - - - 29 42 90 - - - - - 22 19 26 8 - - 31 2 T56 SVSMPAET AHISSPH 2 41 33 - - - - - - - - - - - 4 4 - - - - - - S60 PAETAHIS SPHHELR 6 123 7 - - - 15 12 37 - - - - - 20 20 6 2 - - 4 - S61 AETAHISS PHHELRR 5 148 6 - - - 11 7 91 - - - - - - - 21 4 - - 6 2 S76 PVLQRQTS ITQTIRR 7 660 - - - - 92 96 99 - 11 8 - - 22 20 64 14 86 35 95 18 T85 TQTIRRGT ADWFGVS 4 57 - - 17 8 - - - - - - - - 8 8 7 1 - - 5 3
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S8 MSEARRDS TSSLQRK -0.83 - - - - - - - -0.83 - - T9 SEARRDST SSLQRKK - - - - - - - - - - - S10 EARRDSTS SLQRKKP - - - - - - - - - - - S11 ARRDSTSS LQRKKPP -3.8e-7 - -3.8e-7 - - - - - - - - S51 QAFLRSVS MPAETAH 0.54 - - -0.35 - - - 0.073 - - - T56 SVSMPAET AHISSPH - - - - - - - - - - - S60 PAETAHIS SPHHELR -0.012 - - - - - - -0.012 - - - S61 AETAHISS PHHELRR - - - - - - - - - - - S76 PVLQRQTS ITQTIRR 0.056 - - 4.3e-6 - - - 0.21 -0.16 3.3e-10 -1.3e-10 T85 TQTIRRGT ADWFGVS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S8
T9
S10
S11
S51
T56
S60
S61
S76
T85
S92
S128
S133
T135
S136
T137
T139
T171
S176
T180
T183
S188
S191
S210
S227
S240
S245
Y276
S283
S346
T383
S390
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation CCRCC S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation COAD S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation GBM S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation HNSCC S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation LSCC S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation LUAD S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation OV S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation PDAC S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation UCEC S8 T9 S10 S11 S51 T56 S60 S61 S76 T85 S92 S128 S133 T135 S136 T137 T139 T171 S176 T180 T183 S188 S191 S210 S227 S240 S245 Y276 S283 S346 T383 S390 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S8
T9
S10
S11
S51
T56
S60
S61
S76
T85
S92
S128
S133
T135
S136
T137
T139
T171
S176
T180
T183
S188
S191
S210
S227
S240
S245
Y276
S283
S346
T383
S390
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S8
T9
S10
S11
S51
T56
S60
S61
S76
T85
S92
S128
S133
T135
S136
T137
T139
T171
S176
T180
T183
S188
S191
S210
S227
S240
S245
Y276
S283
S346
T383
S390
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.