N4BP1: NEDD4 binding protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S101 AESLFLKS LIQDTCA 1 31 - - 16 15 - - - - - - - - - - - - - - - - S123 GLLGIRGS AEAVVMA 1 39 - - 20 19 - - - - - - - - - - - - - - - - T221 EFTQNAAT GLNISRD 2 23 - - - - - - - - - - - - 9 7 - - - - 5 2 S226 AATGLNIS RDETVLQ 6 77 6 - - - - - 8 - 16 11 10 10 - - 6 1 - - 7 2 T230 LNISRDET VLQEEAR 1 8 - - - - - - - - - - 5 3 - - - - - - - - T242 EARNKAGT PVSELTK 10 1476 115 - 95 80 97 100 99 - 74 44 103 94 110 101 83 19 105 44 95 18 S245 NKAGTPVS ELTKQMD 5 38 9 - - - 5 4 - - - - 4 4 - - - - 4 2 6 - T253 ELTKQMDT VLSSSPD 1 6 6 - - - - - - - - - - - - - - - - - - - S256 KQMDTVLS SSPDVLF 1 8 - - 4 4 - - - - - - - - - - - - - - - - S257 QMDTVLSS SPDVLFD 1 7 - - - - - - - - - - - - - - - - 5 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S101 AESLFLKS LIQDTCA - - - - - - - - - - - S123 GLLGIRGS AEAVVMA 0.014 - 0.014 - - - - - - - - T221 EFTQNAAT GLNISRD - - - - - - - - - - - S226 AATGLNIS RDETVLQ - - - - - - - - - - - T230 LNISRDET VLQEEAR - - - - - - - - - - - T242 EARNKAGT PVSELTK 8.3e-6 - 1.3e-11 -0.22 - 1.5e-4 -0.63 0.31 -0.59 7.9e-14 -2.7e-5 S245 NKAGTPVS ELTKQMD - - - - - - - - - - - T253 ELTKQMDT VLSSSPD - - - - - - - - - - - S256 KQMDTVLS SSPDVLF - - - - - - - - - - - S257 QMDTVLSS SPDVLFD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S101
S123
T221
S226
T230
T242
S245
T253
S256
S257
S258
S277
S288
S300
S325
S327
S328
S331
S335
S398
T401
Y403
S417
T418
T422
T423
T426
S456
T489
S493
S495
S498
S500
S508
S512
S513
S551
S562
S573
S838
S851
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation CCRCC S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation COAD S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation GBM S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation HNSCC S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation LSCC S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation LUAD S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation OV S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation PDAC S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation UCEC S101 S123 T221 S226 T230 T242 S245 T253 S256 S257 S258 S277 S288 S300 S325 S327 S328 S331 S335 S398 T401 Y403 S417 T418 T422 T423 T426 S456 T489 S493 S495 S498 S500 S508 S512 S513 S551 S562 S573 S838 S851 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S101
S123
T221
S226
T230
T242
S245
T253
S256
S257
S258
S277
S288
S300
S325
S327
S328
S331
S335
S398
T401
Y403
S417
T418
T422
T423
T426
S456
T489
S493
S495
S498
S500
S508
S512
S513
S551
S562
S573
S838
S851
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S101
S123
T221
S226
T230
T242
S245
T253
S256
S257
S258
S277
S288
S300
S325
S327
S328
S331
S335
S398
T401
Y403
S417
T418
T422
T423
T426
S456
T489
S493
S495
S498
S500
S508
S512
S513
S551
S562
S573
S838
S851
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.