CELSR1: cadherin EGF LAG seven-pass G-type receptor 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S704 NEDAAVGS SVLTLQA 2 15 - - - - - - - - - - - - 4 4 - - 5 2 - - T721 RDANSVIT YQLTGGN 1 7 - - - - - - - - - - - - - - - - 5 2 - - T729 YQLTGGNT RNRFALS 1 8 - - - - - - - - - - - - 4 4 - - - - - - S2726 RKLHLEDS ATTRATL 3 178 - - - - - - - - 6 4 45 41 - - - - - - 64 18 S2737 RATLLTRS LNCNTTF 3 61 - - 4 4 - - - - - - - - - - 8 1 - - 38 6 S2758 LRTDLGES TASLDSI 7 217 - - 33 29 12 6 - - 7 3 30 28 16 16 - - 8 3 13 13 T2759 RTDLGEST ASLDSIV 9 282 14 - 60 45 12 6 9 - 13 7 5 5 16 16 - - 8 3 47 16 S2761 DLGESTAS LDSIVRD 10 1054 105 - 99 76 34 37 18 - 103 59 98 91 57 51 83 19 11 6 89 18 S2764 ESTASLDS IVRDEGI 10 680 48 - 37 26 34 37 9 - 54 27 40 35 32 29 52 14 79 34 78 15 S2784 SSGLVRGS HGEPDAS 1 52 - - - - - - - - - - - - - - 43 9 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S704 NEDAAVGS SVLTLQA - - - - - - - - - - - T721 RDANSVIT YQLTGGN - - - - - - - - - - - T729 YQLTGGNT RNRFALS - - - - - - - - - - - S2726 RKLHLEDS ATTRATL 2.7e-5 - - - - - 2e-9 - - - -0.95 S2737 RATLLTRS LNCNTTF - - - - - - - - - - - S2758 LRTDLGES TASLDSI 0.048 - -0.24 - - - 7.1e-5 - - - - T2759 RTDLGEST ASLDSIV -0.014 - -0.52 - - - - - - - -4.8e-3 S2761 DLGESTAS LDSIVRD 1.1e-5 - 0.56 7.5e-4 - 0.77 1.6e-10 0.87 0.37 - -0.96 S2764 ESTASLDS IVRDEGI 0.06 - 0.56 7.5e-4 - -0.66 -0.029 -2.6e-10 1.3e-3 2.6e-13 -0.81 S2784 SSGLVRGS HGEPDAS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S704
T721
T729
S2726
S2737
S2758
T2759
S2761
S2764
S2784
T2849
S2867
S2871
S2873
S2889
S2899
S2960
S2967
S2968
S2971
S2982
S3009
S3011
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation CCRCC S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation COAD S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation GBM S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation HNSCC S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation LSCC S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation LUAD S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation OV S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation PDAC S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation UCEC S704 T721 T729 S2726 S2737 S2758 T2759 S2761 S2764 S2784 T2849 S2867 S2871 S2873 S2889 S2899 S2960 S2967 S2968 S2971 S2982 S3009 S3011 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S704
T721
T729
S2726
S2737
S2758
T2759
S2761
S2764
S2784
T2849
S2867
S2871
S2873
S2889
S2899
S2960
S2967
S2968
S2971
S2982
S3009
S3011
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S704
T721
T729
S2726
S2737
S2758
T2759
S2761
S2764
S2784
T2849
S2867
S2871
S2873
S2889
S2899
S2960
S2967
S2968
S2971
S2982
S3009
S3011
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.