MAST3: microtubule associated serine/threonine kinase 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1v9v chain A
3khf chain A
3khf chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S32 CRSGNRKS LVVGTPS 1 8 8 - - - - - - - - - - - - - - - - - - - S39 SLVVGTPS PTLSRPL 4 40 - - 4 2 - - - - - - 5 5 - - - - 7 3 11 3 T41 VVGTPSPT LSRPLSP 2 19 - - - - - - - - 6 4 - - - - - - 5 4 - - S43 GTPSPTLS RPLSPLS 1 5 - - - - - - - - - - - - - - - - 4 1 - - S47 PTLSRPLS PLSVPTA 9 607 65 - 43 35 - - 17 - 30 17 64 59 72 65 23 4 64 29 20 - S50 SRPLSPLS VPTAGSS 4 42 8 - 4 4 - - - - - - 9 9 4 4 - - - - - - T53 LSPLSVPT AGSSPLD 2 17 - - - - - - - - - - - - 4 4 - - - - 7 2 S56 LSVPTAGS SPLDSPR 2 16 - - 4 4 - - - - - - - - 4 4 - - - - - - S57 SVPTAGSS PLDSPRN 7 194 - - 8 8 - - 35 - - - 10 9 10 8 14 2 37 17 27 9 S61 AGSSPLDS PRNFSAA 2 15 - - - - - - - - - - - - - - - - 5 4 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S32 CRSGNRKS LVVGTPS - - - - - - - - - - - S39 SLVVGTPS PTLSRPL - - - - - - - - - - - T41 VVGTPSPT LSRPLSP - - - - - - - - - - - S43 GTPSPTLS RPLSPLS - - - - - - - - - - - S47 PTLSRPLS PLSVPTA -1.2e-9 - 9.5e-6 - - -0.028 -2.5e-4 -1.3e-8 - -9.1e-11 - S50 SRPLSPLS VPTAGSS - - - - - - - - - - - T53 LSPLSVPT AGSSPLD - - - - - - - - - - - S56 LSVPTAGS SPLDSPR - - - - - - - - - - - S57 SVPTAGSS PLDSPRN -4.6e-8 - - - - - - - - -4.6e-8 - S61 AGSSPLDS PRNFSAA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S32
S39
T41
S43
S47
S50
T53
S56
S57
S61
S66
S85
S88
Y94
T98
T102
S104
S105
S106
S109
T121
S134
S135
S146
S348
T543
S680
T685
S705
S709
S710
S711
T719
T721
S726
S728
S747
S754
S757
S760
S774
S776
T780
S782
S792
S793
S830
S847
S881
S882
S885
S889
S896
S898
S900
S903
T907
S921
S934
S935
S1084
S1089
S1091
S1101
S1109
T1134
S1136
S1141
S1180
S1183
S1201
S1203
S1215
S1223
S1257
S1273
T1286
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation CCRCC S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation COAD S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation GBM S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation HNSCC S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation LSCC S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation LUAD S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation OV S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation PDAC S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation UCEC S32 S39 T41 S43 S47 S50 T53 S56 S57 S61 S66 S85 S88 Y94 T98 T102 S104 S105 S106 S109 T121 S134 S135 S146 S348 T543 S680 T685 S705 S709 S710 S711 T719 T721 S726 S728 S747 S754 S757 S760 S774 S776 T780 S782 S792 S793 S830 S847 S881 S882 S885 S889 S896 S898 S900 S903 T907 S921 S934 S935 S1084 S1089 S1091 S1101 S1109 T1134 S1136 S1141 S1180 S1183 S1201 S1203 S1215 S1223 S1257 S1273 T1286 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S32
S39
T41
S43
S47
S50
T53
S56
S57
S61
S66
S85
S88
Y94
T98
T102
S104
S105
S106
S109
T121
S134
S135
S146
S348
T543
S680
T685
S705
S709
S710
S711
T719
T721
S726
S728
S747
S754
S757
S760
S774
S776
T780
S782
S792
S793
S830
S847
S881
S882
S885
S889
S896
S898
S900
S903
T907
S921
S934
S935
S1084
S1089
S1091
S1101
S1109
T1134
S1136
S1141
S1180
S1183
S1201
S1203
S1215
S1223
S1257
S1273
T1286
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S32
S39
T41
S43
S47
S50
T53
S56
S57
S61
S66
S85
S88
Y94
T98
T102
S104
S105
S106
S109
T121
S134
S135
S146
S348
T543
S680
T685
S705
S709
S710
S711
T719
T721
S726
S728
S747
S754
S757
S760
S774
S776
T780
S782
S792
S793
S830
S847
S881
S882
S885
S889
S896
S898
S900
S903
T907
S921
S934
S935
S1084
S1089
S1091
S1101
S1109
T1134
S1136
S1141
S1180
S1183
S1201
S1203
S1215
S1223
S1257
S1273
T1286
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.