CCDC6: coiled-coil domain containing 6
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S4 ____MADS ASESDTD 1 6 - - - - - - - - - - - - - - - - - - 6 - S46 GGGGGGKS GGIVISP 3 61 - - - - - - - - - - 10 8 - - 28 6 - - 7 2 S52 KSGGIVIS PFRLEEL 10 1517 122 - 99 78 92 87 99 - 108 62 108 99 110 101 75 16 105 43 95 18 T60 PFRLEELT NRLASLQ 1 8 - - - - - - - - - - - - - - 7 1 - - - - S98 NRDLRKAS VTIQARA 9 448 22 - 25 21 8 10 63 - 72 44 - - 40 35 21 4 5 1 61 16 S240 EKLDQPVS APPSPRD 10 853 121 - 41 21 18 9 64 - 42 22 98 89 47 44 83 19 16 6 95 18 S244 QPVSAPPS PRDISME 10 1553 122 - 103 80 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 S249 PPSPRDIS MEIDSPE 2 28 9 - - - - - - - - - 10 9 - - - - - - - - S254 DISMEIDS PENMMRH 10 806 104 - 5 4 4 5 72 - 56 34 103 95 66 62 61 15 9 3 90 18 S284 RAAQLQHS EKMAQYL 5 97 36 - - - - - 27 - - - 10 8 - - 7 2 - - 5 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S4 ____MADS ASESDTD - - - - - - - - - - - S46 GGGGGGKS GGIVISP - - - - - - - - - - - S52 KSGGIVIS PFRLEEL 4.8e-109 - 5.8e-16 3.8e-18 - 2.7e-7 2e-32 3.1e-29 3.5e-5 3.6e-16 4.8e-8 T60 PFRLEELT NRLASLQ - - - - - - - - - - - S98 NRDLRKAS VTIQARA 1.2e-3 - 1.6e-6 - - 0.1 - 0.13 - - -0.14 S240 EKLDQPVS APPSPRD 0.034 - 0.31 - - 1.7e-4 -0.21 0.94 0.54 - 0.32 S244 QPVSAPPS PRDISME -0.36 - -1.6e-8 3.0e-4 - -6.2e-6 -0.15 6.6e-11 0.62 -1e-8 4.3e-5 S249 PPSPRDIS MEIDSPE - - - - - - - - - - - S254 DISMEIDS PENMMRH 0.78 - - - - -5.7e-3 0.017 0.055 -0.95 - -0.39 S284 RAAQLQHS EKMAQYL - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S4
S46
S52
T60
S98
S240
S244
S249
S254
S284
S323
S325
S327
S328
Y336
S341
S351
S352
Y356
T357
S359
S361
S363
S367
S371
Y372
S374
T376
T380
S413
S417
S419
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation CCRCC S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation COAD S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation GBM S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation HNSCC S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation LSCC S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation LUAD S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation OV S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation PDAC S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation UCEC S4 S46 S52 T60 S98 S240 S244 S249 S254 S284 S323 S325 S327 S328 Y336 S341 S351 S352 Y356 T357 S359 S361 S363 S367 S371 Y372 S374 T376 T380 S413 S417 S419 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S4
S46
S52
T60
S98
S240
S244
S249
S254
S284
S323
S325
S327
S328
Y336
S341
S351
S352
Y356
T357
S359
S361
S363
S367
S371
Y372
S374
T376
T380
S413
S417
S419
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S4
S46
S52
T60
S98
S240
S244
S249
S254
S284
S323
S325
S327
S328
Y336
S341
S351
S352
Y356
T357
S359
S361
S363
S367
S371
Y372
S374
T376
T380
S413
S417
S419
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.