CABIN1: calcineurin binding protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S11 IAALNASS TIEDDHE 4 63 - - - - - - - - 17 12 - - 5 4 14 4 - - 5 2 T12 AALNASST IEDDHEG 4 44 9 - - - - - - - 11 8 - - - - 8 1 - - 5 2 S20 IEDDHEGS FKSHKTQ 3 23 6 - - - - - - - 7 2 - - - - 7 1 - - - - S66 YHELLEAS LLREAVS 5 93 24 - 9 8 4 5 - - - - - - 18 16 - - - - - 9 S383 GVKRKKIS EESGETA 1 6 6 - - - - - - - - - - - - - - - - - - - S433 DPEEEDDS FNNYEVQ 10 541 49 - 25 15 16 20 46 - 72 45 49 45 22 20 7 1 23 9 59 18 Y437 EDDSFNNY EVQSEAK 4 53 26 - 4 4 - - - - 7 3 - - 5 4 - - - - - - S450 AKLESFPS IGPQRLS 2 28 - - - - - - - - - - 5 4 - - - - - - 14 5 S457 SIGPQRLS FDSATFM 5 208 - - 9 8 - - - - 67 39 15 13 27 24 - - 4 2 - - T462 RLSFDSAT FMESEKQ 1 10 - - - - - - - - - - 5 5 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S11 IAALNASS TIEDDHE - - - - - - - - - - - T12 AALNASST IEDDHEG - - - - - - - - - - - S20 IEDDHEGS FKSHKTQ - - - - - - - - - - - S66 YHELLEAS LLREAVS - - - - - - - - - - - S383 GVKRKKIS EESGETA - - - - - - - - - - - S433 DPEEEDDS FNNYEVQ 2.2e-7 - -0.088 - - 4.3e-5 2e-23 0.43 - - -0.12 Y437 EDDSFNNY EVQSEAK - - - - - - - - - - - S450 AKLESFPS IGPQRLS - - - - - - - - - - - S457 SIGPQRLS FDSATFM 0.052 - - - - 4.4e-3 - -0.92 - - - T462 RLSFDSAT FMESEKQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S11
T12
S20
S66
S383
S433
Y437
S450
S457
T462
S564
S567
S1182
S1323
S1326
S1347
S1375
S1439
S1442
T1474
S1695
S1740
T1763
S1764
T1767
S1771
T1776
T1814
S1841
S1921
T1924
T1926
T1927
S2026
S2045
T2060
S2093
S2094
T2151
T2154
T2156
S2159
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation CCRCC S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation COAD S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation GBM S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation HNSCC S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation LSCC S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation LUAD S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation OV S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation PDAC S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation UCEC S11 T12 S20 S66 S383 S433 Y437 S450 S457 T462 S564 S567 S1182 S1323 S1326 S1347 S1375 S1439 S1442 T1474 S1695 S1740 T1763 S1764 T1767 S1771 T1776 T1814 S1841 S1921 T1924 T1926 T1927 S2026 S2045 T2060 S2093 S2094 T2151 T2154 T2156 S2159 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S11
T12
S20
S66
S383
S433
Y437
S450
S457
T462
S564
S567
S1182
S1323
S1326
S1347
S1375
S1439
S1442
T1474
S1695
S1740
T1763
S1764
T1767
S1771
T1776
T1814
S1841
S1921
T1924
T1926
T1927
S2026
S2045
T2060
S2093
S2094
T2151
T2154
T2156
S2159
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S11
T12
S20
S66
S383
S433
Y437
S450
S457
T462
S564
S567
S1182
S1323
S1326
S1347
S1375
S1439
S1442
T1474
S1695
S1740
T1763
S1764
T1767
S1771
T1776
T1814
S1841
S1921
T1924
T1926
T1927
S2026
S2045
T2060
S2093
S2094
T2151
T2154
T2156
S2159
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.