Protein: ENSP00000263125
Gene: PRKCQ

LinkedOmicsKB © 2022-2023 Zhang Lab

PRKCQ:
protein kinase C theta

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S19FDCGSCQSCQGEAVN216----------44------8-
S212VIAKCTGSAINSRET16------------------6-
S323VEIGLPCSIKNEARP9104814-10380--63-1035994869284521464279518
S345KREPQGISWESPLDE110--------73----------
S370ELNKERPSLQIKLKI7504--6454----92524326245414639018
T538LGDAKTNTFCGTPDY10138369-7149979890-10862108991101015213105448918
T542KTNTFCGTPDYIAPE19--------54----------
Y545TFCGTPDYIAPEILL227--98------55--------
S676LNEKPRLSFADRALI9557122---6381-4931151469641861564414
S685ADRALINSMDQNMFR9105530-7764--90-10862108998781831932148318
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S19FDCGSCQSCQGEAVN-----------
S212VIAKCTGSAINSRET-----------
S323VEIGLPCSIKNEARP-1e-19--5e-12---0.39-2.2e-7-2.1e-60.96-4.4e-3-3.8e-4
S345KREPQGISWESPLDE-----------
S370ELNKERPSLQIKLKI-4.6e-5--5.8e-15--0.98--0.180.091--0.093
T538LGDAKTNTFCGTPDY-1.6e-24--4.6e-111.4e-10--1.1e-4-1.8e-17-1.5e-170.82-4.3e-5-7.2e-5
T542KTNTFCGTPDYIAPE-----------
Y545TFCGTPDYIAPEILL-----------
S676LNEKPRLSFADRALI-4.6e-7-----0.27--9.8e-8---0.021
S685ADRALINSMDQNMFR-1.2e-20--1.6e-9--0.59-2.4e-14-1.3e-16-0.230.14-4.3e-4
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationCCRCCS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationCOADS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationGBMS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationHNSCCS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationLSCCS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationLUADS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationOVS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationPDACS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylationUCECS19S212S323S345S370T538T542Y545S676S685S695proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.