BAX: BCL2 associated X, apoptosis regulator
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1f16 chain A
2g5b chain I
2g5b chain J
2g5b chain K
2g5b chain L
2k7w chain A
2lr1 chain A
3pk1 chain B
3pk1 chain D
3pl7 chain C
4bd2 chain A
4bd6 chain A
4bd6 chain C
4bd7 chain A
4bd7 chain B
4bd7 chain C
4bd7 chain D
4bd8 chain A
4bd8 chain B
4bd8 chain C
4bd8 chain D
4bdu chain A
4bdu chain B
4bdu chain C
4bdu chain D
4s0o chain A
4s0o chain B
4s0p chain A
4s0p chain B
4uf2 chain B
4zie chain A
4zif chain A
4zig chain A
4zih chain A
4zii chain A
5w5x chain A
5w5z chain A
5w60 chain A
5w61 chain A
6eb6 chain A
6l8v chain A
6l8v chain B
6l95 chain A
6l95 chain B
6trr chain B
6xy6 chain B
6xy6 chain D
6xy6 chain F
6xy6 chain H
6xy6 chain J
6xy6 chain L
6xy6 chain N
6xy6 chain P
7adt chain C
7adt chain U
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S15 PRGGGPTS SEQIMKT 1 9 9 - - - - - - - - - - - - - - - - - - - S55 DPVPQDAS TKKLSEC 1 9 - - - - - - - - - - - - - - - - - - 7 2 S72 RIGDELDS NMELQRM 1 8 - - - - - - - - - - - - 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S15 PRGGGPTS SEQIMKT - - - - - - - - - - - S55 DPVPQDAS TKKLSEC - - - - - - - - - - - S72 RIGDELDS NMELQRM - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S15
S55
S72
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S15 S55 S72 protein RNA SCNV methylation CCRCC S15 S55 S72 protein RNA SCNV methylation COAD S15 S55 S72 protein RNA SCNV methylation GBM S15 S55 S72 protein RNA SCNV methylation HNSCC S15 S55 S72 protein RNA SCNV methylation LSCC S15 S55 S72 protein RNA SCNV methylation LUAD S15 S55 S72 protein RNA SCNV methylation OV S15 S55 S72 protein RNA SCNV methylation PDAC S15 S55 S72 protein RNA SCNV methylation UCEC S15 S55 S72 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S15
S55
S72
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S15
S55
S72
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.