PPP1R12C: protein phosphatase 1 regulatory subunit 12C
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S2 ______MS GEDGPAA 3 32 - - - - 5 4 - - - - - - - - 8 1 - - 11 3 S325 LRNQKEAS QSRGQEP 1 8 8 - - - - - - - - - - - - - - - - - - - S327 NQKEASQS RGQEPQA 1 9 9 - - - - - - - - - - - - - - - - - - - S336 GQEPQAPS SSKHRRS 1 7 - - - - - - - - - - - - 4 3 - - - - - - S337 QEPQAPSS SKHRRSS 1 18 - - - - 11 7 - - - - - - - - - - - - - - S338 EPQAPSSS KHRRSSV 1 6 - - - - - - - - - - - - - - - - - - 6 - S343 SSSKHRRS SVCRLSS 8 414 26 - 25 23 19 21 45 - - - 42 39 14 10 - - 63 25 44 18 S344 SSKHRRSS VCRLSSR 8 433 26 - 25 23 19 21 45 - - - 42 39 14 10 - - 68 26 57 18 S349 RSSVCRLS SREKISL 4 59 8 - 4 4 - - 9 - - - - - 16 18 - - - - - - S350 SSVCRLSS REKISLQ 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S2 ______MS GEDGPAA - - - - - - - - - - - S325 LRNQKEAS QSRGQEP - - - - - - - - - - - S327 NQKEASQS RGQEPQA - - - - - - - - - - - S336 GQEPQAPS SSKHRRS - - - - - - - - - - - S337 QEPQAPSS SKHRRSS - - - - - - - - - - - S338 EPQAPSSS KHRRSSV - - - - - - - - - - - S343 SSSKHRRS SVCRLSS -0.42 - 0.011 - - - -0.07 - - 5.2e-4 -5.7e-9 S344 SSKHRRSS VCRLSSR -0.76 - 0.011 - - - -0.07 - - 5.2e-4 -1.4e-6 S349 RSSVCRLS SREKISL - - - - - - - - - - - S350 SSVCRLSS REKISLQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S2
S325
S327
S336
S337
S338
S343
S344
S349
S350
S355
S398
S399
S404
S407
T425
S427
S428
S452
S453
S454
T472
S476
T489
S498
S499
S509
S532
S559
T560
S647
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation CCRCC S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation COAD S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation GBM S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation HNSCC S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation LSCC S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation LUAD S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation OV S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation PDAC S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation UCEC S2 S325 S327 S336 S337 S338 S343 S344 S349 S350 S355 S398 S399 S404 S407 T425 S427 S428 S452 S453 S454 T472 S476 T489 S498 S499 S509 S532 S559 T560 S647 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S2
S325
S327
S336
S337
S338
S343
S344
S349
S350
S355
S398
S399
S404
S407
T425
S427
S428
S452
S453
S454
T472
S476
T489
S498
S499
S509
S532
S559
T560
S647
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S2
S325
S327
S336
S337
S338
S343
S344
S349
S350
S355
S398
S399
S404
S407
T425
S427
S428
S452
S453
S454
T472
S476
T489
S498
S499
S509
S532
S559
T560
S647
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.