Protein: ENSP00000263674
Gene: ARHGEF17

LinkedOmicsKB © 2022-2023 Zhang Lab

ARHGEF17:
Rho guanine nucleotide exchange factor 17

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S43PGLRRRASCRPTTAA998753-9168768598-422588828882142--7518
S63RRVSKLASGPLAAPA18--44----------------
S79PRPLRSLSPSVRQLS1096725-4237939572-985549444745471283367314
S138KLFGGPGSRRPSADS83788-74553429----15133229401022116-
S142GPGSRRPSADSESPG95406-88535499---26261212511056218216
S145SRRPSADSESPGTPS7227--98--10-1171086256--241093
S147RPSADSESPGTPSPD842123-6753--10-241240376355--421912
T150ADSESPGTPSPDGAA91129-44549-135151554--51113
S152SESPGTPSPDGAAWE330------9-------62--13-
T170RESRQPPTPPPRTCF101502122-103809710099-8047108991101018219100429518
Showing 1 to 10 of 110 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S43PGLRRRASCRPTTAA-4.8e-15-3.7e-12-3.5e-14-0.7-2.1e-13-7.5e-11---3.8e-7
S63RRVSKLASGPLAAPA-----------
S79PRPLRSLSPSVRQLS-1.4e-10-9.7e-7-1.2e-17--0.011-1.5e-16-4.4e-11-0.137.9e-10-0.082
S138KLFGGPGSRRPSADS-1.7e-4-7.5e-8-5e-9----5.1e-11-0.0740.67-
S142GPGSRRPSADSESPG-1.7e-9---8.3e-11---2.1e-6--0.180.13-0.017
S145SRRPSADSESPGTPS-0.14-------2.5e-9-1.1e-4-
S147RPSADSESPGTPSPD-2.2e-6-1.6e-6---0.041-1.4e-8-5.8e-11---
T150ADSESPGTPSPDGAA-----------
S152SESPGTPSPDGAAWE-----------
T170RESRQPPTPPPRTCF-3.7e-20-4.2e-5-2.7e-6-0.037-2.6e-28-1.4e-11-0.031-4.2e-4-5.6e-5
Showing 1 to 10 of 110 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationCCRCCS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationCOADS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationGBMS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationHNSCCS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationLSCCS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationLUADS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationOVS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationPDACS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylationUCECS43S63S79S138S142S145S147T150S152T170S230S232S243S266S274S275S277S310S317S320S324S326S332S346S348S363S376S383S387S391Y393S394S395T396T398S406S407S410S418S420S461S463S493S507S509S527S546S566S567S569S613S619S632S637S715S720S723S733S735T746S747S754S757S762S764T780S781S784S787S790S827S829S860S861S862T879S881S885S914S929S930S940S946S961S1002S1330S1331S1333Y1335T1336T1386S1391S1478T1659S1662S1663T1669S1671S1672S1681S1682S1694S1706S1716S1717S1720S1961T1991S2005S2011proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.