KAT2B: lysine acetyltransferase 2B
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1cm0 chain A
1cm0 chain B
1jm4 chain B
1n72 chain A
1wug chain A
1wum chain A
1zs5 chain A
2rnw chain A
2rnx chain A
3gg3 chain A
3gg3 chain B
4nsq chain A
4nsq chain B
4nsq chain C
4nsq chain D
5fdz chain A
5fdz chain B
5fe0 chain A
5fe0 chain B
5fe1 chain A
5fe1 chain B
5fe2 chain A
5fe2 chain B
5fe3 chain A
5fe3 chain B
5fe4 chain A
5fe4 chain B
5fe5 chain A
5fe5 chain B
5fe6 chain A
5fe6 chain B
5fe7 chain A
5fe7 chain B
5fe8 chain A
5fe8 chain B
5fe9 chain A
5fe9 chain B
5lvq chain A
5lvq chain B
5lvr chain A
5lvr chain B
5mkx chain A
5mkx chain B
6j3o chain A
6j3o chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S117 GWKNPNPS PTPPRAD 7 299 - - - - 26 28 64 - 11 7 25 24 14 11 62 15 - - 12 - T119 KNPNPSPT PPRADLQ 6 389 35 - 24 23 - - - - 29 16 50 44 83 77 5 3 - - - - S270 PSQRRLRS PNDDISG 1 9 - - - - - - - - - - - - - - - - - - 7 2 S410 LEQPNAGS SSPACKA 3 133 - - - - - - - - - - 34 31 33 26 - - - - - 9 S412 QPNAGSSS PACKASS 1 16 - - - - - - - - - - - - - - - - - - 13 3
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S117 GWKNPNPS PTPPRAD -0.011 - - -0.98 - - -0.19 - -2.2e-3 - - T119 KNPNPSPT PPRADLQ -2.6e-5 - 3.3e-3 - - -5.7e-3 -2.5e-4 -8.6e-7 - - - S270 PSQRRLRS PNDDISG - - - - - - - - - - - S410 LEQPNAGS SSPACKA -7.4e-4 - - - - - -4.2e-3 -0.057 - - - S412 QPNAGSSS PACKASS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S117
T119
S270
S410
S412
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S117 T119 S270 S410 S412 protein RNA SCNV methylation CCRCC S117 T119 S270 S410 S412 protein RNA SCNV methylation COAD S117 T119 S270 S410 S412 protein RNA SCNV methylation GBM S117 T119 S270 S410 S412 protein RNA SCNV methylation HNSCC S117 T119 S270 S410 S412 protein RNA SCNV methylation LSCC S117 T119 S270 S410 S412 protein RNA SCNV methylation LUAD S117 T119 S270 S410 S412 protein RNA SCNV methylation OV S117 T119 S270 S410 S412 protein RNA SCNV methylation PDAC S117 T119 S270 S410 S412 protein RNA SCNV methylation UCEC S117 T119 S270 S410 S412 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S117
T119
S270
S410
S412
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S117
T119
S270
S410
S412
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.