Protein: ENSP00000263801
Gene: TP53BP1

LinkedOmicsKB © 2022-2023 Zhang Lab

TP53BP1:
tumor protein p53 binding protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S63NPVLDVVSNPEQTAG1066772-3213231354-241354493533471165288318
T68VVSNPEQTAGEERGD177-------------------
S78EERGDGNSGFNEHLK711523---639---55--142523011
S95KVADPVDSSNLDTCG19----45--------------
S96VADPVDSSNLDTCGS9318--341521159-4929333119163-104237
T100VDSSNLDTCGSISQV19--54----------------
S103SNLDTCGSISQVIEQ729462-1310--18---20204541134--3711
S105LDTCGSISQVIEQLP66423-33----5455--71--53
T117QLPQPNRTSSVLGMS114------------------14-
S119PQPNRTSSVLGMSVE101437122-8260848690-9656103951101017515105449518
Showing 1 to 10 of 198 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S63NPVLDVVSNPEQTAG-5.8e-6--0.069-2.2e-3-0.960.19-0.51-7.5e-3-4.5e-3-1.7e-3
T68VVSNPEQTAGEERGD-----------
S78EERGDGNSGFNEHLK0.78---------0.78
S95KVADPVDSSNLDTCG-----------
S96VADPVDSSNLDTCGS-2.2e-3--0.68-0.21--8.0e-5-0.6----
T100VDSSNLDTCGSISQV-----------
S103SNLDTCGSISQVIEQ-0.26------0.043-6.2e-3--4.8e-3
S105LDTCGSISQVIEQLP-----------
T117QLPQPNRTSSVLGMS-----------
S119PQPNRTSSVLGMSVE1.4e-23-0.162.6e-5-0.171.3e-135.6e-130.0671.5e-10-0.13
Showing 1 to 10 of 198 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

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

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.