EHBP1: EH domain binding protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2d89 chain A
6zsh chain A
6zsh chain B
6zsh chain C
6zsh chain D
6zsi chain C
6zsi chain D
6zsj chain C
6zsj chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S106 TFVIENES PSGRRKA 4 90 - - - - - - 27 - - - 5 4 10 8 - - - - 30 6 S171 ATDEDMQS LASLMSM 10 1331 88 - 91 68 90 90 90 - 103 58 103 94 110 101 20 4 86 36 81 18 S174 EDMQSLAS LMSMKQA 9 769 39 - 8 7 97 100 36 - 85 49 84 77 34 32 - - 40 18 49 14 S177 QSLASLMS MKQADIG 6 82 30 - - - - - 9 - - - 5 5 4 4 - - 8 5 12 - S222 NQLNALSS LDEDQDD 1 9 - - - - - - 9 - - - - - - - - - - - - - S241 ANMRSAKS ASSSEEL 1 27 - - - - - - 27 - - - - - - - - - - - - - S244 RSAKSASS SEELINK 1 18 - - - - - - 18 - - - - - - - - - - - - - S245 SAKSASSS EELINKL 1 99 - - - - - - 99 - - - - - - - - - - - - - S267 KDLATVNS NPFDDPD 2 17 - - 5 4 - - - - - - 4 4 - - - - - - - - S286 NPFGDPDS EEPITET 4 61 14 - 16 13 4 5 - - 6 3 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S106 TFVIENES PSGRRKA - - - - - - - - - - - S171 ATDEDMQS LASLMSM -2.4e-4 - 0.59 -0.054 - -6.4e-6 0.029 -2.6e-15 - 1.1e-9 -2.6e-5 S174 EDMQSLAS LMSMKQA 0.48 - - -4.7e-11 - -0.52 6.2e-6 -1.9e-5 - 1.9e-10 0.019 S177 QSLASLMS MKQADIG - - - - - - - - - - - S222 NQLNALSS LDEDQDD - - - - - - - - - - - S241 ANMRSAKS ASSSEEL - - - - - - - - - - - S244 RSAKSASS SEELINK - - - - - - - - - - - S245 SAKSASSS EELINKL - - - - - - - - - - - S267 KDLATVNS NPFDDPD - - - - - - - - - - - S286 NPFGDPDS EEPITET - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S106
S171
S174
S177
S222
S241
S244
S245
S267
S286
S295
S302
S307
Y308
T331
S335
S339
S358
S359
S377
T378
S408
S426
T427
S428
S432
S436
S577
S578
Y585
S649
S660
T663
S664
S666
S673
T675
T694
S698
S710
S742
S747
S751
S757
S759
S767
S769
S787
T795
S812
S854
S887
S903
S964
S1019
S1021
Y1023
S1035
S1058
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation CCRCC S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation COAD S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation GBM S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation HNSCC S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation LSCC S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation LUAD S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation OV S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation PDAC S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation UCEC S106 S171 S174 S177 S222 S241 S244 S245 S267 S286 S295 S302 S307 Y308 T331 S335 S339 S358 S359 S377 T378 S408 S426 T427 S428 S432 S436 S577 S578 Y585 S649 S660 T663 S664 S666 S673 T675 T694 S698 S710 S742 S747 S751 S757 S759 S767 S769 S787 T795 S812 S854 S887 S903 S964 S1019 S1021 Y1023 S1035 S1058 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S106
S171
S174
S177
S222
S241
S244
S245
S267
S286
S295
S302
S307
Y308
T331
S335
S339
S358
S359
S377
T378
S408
S426
T427
S428
S432
S436
S577
S578
Y585
S649
S660
T663
S664
S666
S673
T675
T694
S698
S710
S742
S747
S751
S757
S759
S767
S769
S787
T795
S812
S854
S887
S903
S964
S1019
S1021
Y1023
S1035
S1058
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S106
S171
S174
S177
S222
S241
S244
S245
S267
S286
S295
S302
S307
Y308
T331
S335
S339
S358
S359
S377
T378
S408
S426
T427
S428
S432
S436
S577
S578
Y585
S649
S660
T663
S664
S666
S673
T675
T694
S698
S710
S742
S747
S751
S757
S759
S767
S769
S787
T795
S812
S854
S887
S903
S964
S1019
S1021
Y1023
S1035
S1058
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.