Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1b47 chain A
1b47 chain B
1b47 chain C
1fbv chain A
1yvh chain A
2cbl chain A
2juj chain A
2k4d chain A
2oo9 chain A
2oo9 chain B
2oo9 chain C
2y1m chain A
2y1m chain B
2y1m chain C
2y1m chain D
2y1m chain E
2y1m chain F
2y1n chain A
2y1n chain C
3bum chain B
3bun chain B
3buo chain B
3buo chain D
3buw chain B
3buw chain D
3bux chain B
3bux chain D
3ob1 chain B
3ob2 chain B
3plf chain B
3plf chain D
4a49 chain A
4a4b chain A
4a4c chain A
4gpl chain B
5hkw chain A
5hkw chain B
5hkw chain C
5hkx chain A
5hky chain A
5hkz chain A
5hl0 chain A
5j3x chain A
5j3x chain B
5j3x chain C
5j3x chain D
5j3x chain E
5j3x chain F
5o76 chain A
5o76 chain C
6o02 chain A
6o03 chain A
6o03 chain B
6xar chain A
6xar chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S15 SSGAGGGS GSGGSGS 1 9 - - - - - - 9 - - - - - - - - - - - - - S17 GAGGGSGS GGSGSGG 5 261 - - - - - - 62 - 6 4 20 19 58 52 - - - - 34 6 S20 GGSGSGGS GSGGLIG 4 69 9 - - - - - - - - - - - 17 16 - - 4 2 16 5 S22 SGSGGSGS GGLIGLM 5 59 - - 4 4 - - 9 - - - 10 9 8 7 - - 6 2 - - S439 DPFDPRGS GSLLRQG 10 1058 104 - 66 44 25 29 90 - 92 51 98 91 106 97 35 7 22 10 78 13 S441 FDPRGSGS LLRQGAE 9 405 33 - 29 28 22 23 - - 56 33 29 28 9 8 28 6 43 15 6 9 S452 QGAEGAPS PNYDDDD 10 759 58 - 16 8 13 14 81 - 54 28 89 82 55 48 16 7 61 28 83 18 Y455 EGAPSPNY DDDDDER 5 153 41 - 20 11 - - - - 5 4 19 19 18 16 - - - - - - T466 DDERADDT LFMMKEL 2 17 - - - - - - - - - - 5 5 - - - - - - 7 - S483 AKVERPPS PFSMAPQ 10 1536 122 - 94 72 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S15 SSGAGGGS GSGGSGS - - - - - - - - - - - S17 GAGGGSGS GGSGSGG -6.7e-4 - - - - - -0.26 -2.3e-4 - - - S20 GGSGSGGS GSGGLIG - - - - - - - - - - - S22 SGSGGSGS GGLIGLM - - - - - - - - - - - S439 DPFDPRGS GSLLRQG 5.9e-14 - 0.84 0.031 - 5e-8 1.5e-5 5.4e-3 - 0.031 5.2e-3 S441 FDPRGSGS LLRQGAE 1.8e-14 - 5.9e-7 0.33 - 6.1e-13 -0.2 - - 1.6e-7 - S452 QGAEGAPS PNYDDDD -0.39 - - - - 0.4 -1.9e-6 -3.6e-3 - 7.6e-8 -0.65 Y455 EGAPSPNY DDDDDER 0.023 - 0.023 - - - - - - - - T466 DDERADDT LFMMKEL - - - - - - - - - - - S483 AKVERPPS PFSMAPQ -0.93 - 9.9e-8 -0.25 - 1.9e-8 -1.5e-7 -3.4e-20 0.58 -0.88 4.3e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S15
S17
S20
S22
S439
S441
S452
Y455
T466
S483
S486
S526
T568
S601
S619
S623
S626
S639
T640
S642
T645
S646
S648
S651
S667
S668
S669
Y674
Y700
S714
T789
S791
S794
S797
S798
S799
S804
T810
S833
S839
Y869
S870
S900
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation CCRCC S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation COAD S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation GBM S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation HNSCC S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation LSCC S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation LUAD S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation OV S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation PDAC S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation UCEC S15 S17 S20 S22 S439 S441 S452 Y455 T466 S483 S486 S526 T568 S601 S619 S623 S626 S639 T640 S642 T645 S646 S648 S651 S667 S668 S669 Y674 Y700 S714 T789 S791 S794 S797 S798 S799 S804 T810 S833 S839 Y869 S870 S900 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S15
S17
S20
S22
S439
S441
S452
Y455
T466
S483
S486
S526
T568
S601
S619
S623
S626
S639
T640
S642
T645
S646
S648
S651
S667
S668
S669
Y674
Y700
S714
T789
S791
S794
S797
S798
S799
S804
T810
S833
S839
Y869
S870
S900
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S15
S17
S20
S22
S439
S441
S452
Y455
T466
S483
S486
S526
T568
S601
S619
S623
S626
S639
T640
S642
T645
S646
S648
S651
S667
S668
S669
Y674
Y700
S714
T789
S791
S794
S797
S798
S799
S804
T810
S833
S839
Y869
S870
S900
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.