ARID4B: AT-rich interaction domain 4B
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S105 EKTLRRSS LCLKGER 7 614 72 - 44 28 - - - - 50 29 59 54 89 81 - - 49 21 29 9 T126 TLDQLPLT NPEHFGT 1 9 9 - - - - - - - - - - - - - - - - - - - S273 KTELKEDS SSSEAEE 6 56 17 - 5 4 - - - - 6 4 5 4 - - - - 3 2 6 - S274 TELKEDSS SSEAEEE 8 764 61 - 53 42 - - 18 - 67 39 74 63 83 76 - - 85 34 51 18 S275 ELKEDSSS SEAEEEE 8 703 79 - 4 4 - - 18 - 67 39 78 67 83 76 - - 85 34 51 18 S276 LKEDSSSS EAEEEEE 8 600 7 - 53 42 - - 18 - 11 7 59 56 83 76 - - 85 34 51 18 S295 EKEKEDNS SEEEEEI 8 1089 113 - 99 76 - - 99 - 108 62 103 94 98 88 - - 94 40 11 4 S296 KEKEDNSS EEEEEIE 9 1280 113 - 103 80 - - 99 - 108 62 108 98 110 101 33 8 105 44 90 18 S376 LGIPVLNS AAGYNVK 4 171 7 - - - - - - - - - 20 19 62 57 - - - - 6 - S471 NIKPSLGS KKNLLES 8 527 40 - 18 16 - - 9 - 19 7 69 63 85 76 - - 74 29 18 4
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S105 EKTLRRSS LCLKGER 0.82 - 0.78 - - 0.063 -0.18 -0.24 - 0.37 - T126 TLDQLPLT NPEHFGT - - - - - - - - - - - S273 KTELKEDS SSSEAEE - - - - - - - - - - - S274 TELKEDSS SSEAEEE 7.9e-19 - -0.42 - - 1e-7 7.2e-23 1.4e-14 - 0.12 -0.057 S275 ELKEDSSS SEAEEEE 1.6e-24 - - - - 1e-7 3.7e-24 1.4e-14 - 0.11 -0.057 S276 LKEDSSSS EAEEEEE 3.2e-11 - -0.42 - - - 1.4e-16 1.4e-14 - 0.11 -0.057 S295 EKEKEDNS SEEEEEI 1.9e-22 - 0.14 - - 5.3e-10 3.6e-20 3.4e-15 - -0.003 - S296 KEKEDNSS EEEEEIE 2.9e-27 - -0.035 - - 1.5e-5 4e-25 4e-30 - 0.18 0.25 S376 LGIPVLNS AAGYNVK -8.5e-23 - - - - - -3.5e-8 -5e-17 - - - S471 NIKPSLGS KKNLLES 5.0e-6 - - - - - 2.1e-11 3.7e-4 - -0.018 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S105
T126
S273
S274
S275
S276
S295
S296
S376
S471
T481
S483
S656
S666
T672
S675
S713
S717
S736
S778
S790
T793
Y795
S838
S912
T1022
T1025
T1026
S1029
S1031
S1060
S1152
S1153
S1155
S1159
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation CCRCC S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation COAD S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation GBM S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation HNSCC S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation LSCC S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation LUAD S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation OV S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation PDAC S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation UCEC S105 T126 S273 S274 S275 S276 S295 S296 S376 S471 T481 S483 S656 S666 T672 S675 S713 S717 S736 S778 S790 T793 Y795 S838 S912 T1022 T1025 T1026 S1029 S1031 S1060 S1152 S1153 S1155 S1159 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S105
T126
S273
S274
S275
S276
S295
S296
S376
S471
T481
S483
S656
S666
T672
S675
S713
S717
S736
S778
S790
T793
Y795
S838
S912
T1022
T1025
T1026
S1029
S1031
S1060
S1152
S1153
S1155
S1159
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S105
T126
S273
S274
S275
S276
S295
S296
S376
S471
T481
S483
S656
S666
T672
S675
S713
S717
S736
S778
S790
T793
Y795
S838
S912
T1022
T1025
T1026
S1029
S1031
S1060
S1152
S1153
S1155
S1159
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.