Protein: ENSP00000264211
Gene: EIF4G3

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF4G3:
eukaryotic translation initiation factor 4 gamma 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T168GGGSRNPTPPIGRPT6281----443728-1173026--5711--1911
S230KPDPVLKSPSPVLRL7936--7759--44-10862797310293--89379518
S232DPVLKSPSPVLRLVL91400--86719710099-10862108991101018319101439518
S240PVLRLVLSGEKKEQE5196----3933----29282320133--53
S267AELPLPPSPTTVSSV6111----71126---2523541----9
S288APTSSALSSQPIFTT213--44------------41--
S304IDDRCELSSPREDTI7415----191762-24144441--7-73306816
S305DDRCELSSPREDTIP9293--88131443-5424211213771672179
T310LSSPREDTIPIPSLT225----27----88--------
S323LTSCTETSDPLPTNE16----------------51--
Showing 1 to 10 of 40 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T168GGGSRNPTPPIGRPT8.4e-6--3.1e-3--0.013-0.024--
S230KPDPVLKSPSPVLRL9.4e-16-1.8e-9--0.130.24.1e-4-4.2e-41.6e-4
S232DPVLKSPSPVLRLVL1.1e-15-2.8e-8-0.17-6e-141.5e-22-3.5e-100.192.3e-14-0.14
S240PVLRLVLSGEKKEQE2.8e-5--0.84--6.1e-60.012---
S267AELPLPPSPTTVSSV-0.59------0.59----
S288APTSSALSSQPIFTT-----------
S304IDDRCELSSPREDTI1.5e-3----0.240.044--9.3e-30.58
S305DDRCELSSPREDTIP1.8e-3-----0.011-0.06--
T310LSSPREDTIPIPSLT-----------
S323LTSCTETSDPLPTNE-----------
Showing 1 to 10 of 40 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationCCRCCT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationCOADT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationGBMT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationHNSCCT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationLSCCT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationLUADT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationOVT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationPDACT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylationUCECT168S230S232S240S267S288S304S305T310S323T353S371S487S492S495S536S559S585S594T678S719S741S1074S1094S1110S1112S1115T1116S1131S1156S1157S1165S1190S1218S1407S1409S1412S1413S1417S1582proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.