SLAIN2: SLAIN motif family member 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3rdv chain E
3rdv chain F
3rdv chain G
3rdv chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S43 GAVQGAGS LGPGSPV 2 35 - - - - - - - - 16 11 - - - - - - - - 5 3 S48 AGSLGPGS PVRAGAS 10 1310 63 - 69 48 89 81 80 - 108 62 88 78 101 93 83 19 96 39 95 18 S55 SPVRAGAS IPSSGAA 1 8 - - - - - - - - - - - - - - - - - - 5 3 S58 RAGASIPS SGAASPR 2 26 - - - - - - - - 9 8 5 4 - - - - - - - - S59 AGASIPSS GAASPRG 2 44 - - - - - - - - 21 14 5 4 - - - - - - - - S63 IPSSGAAS PRGFPLG 10 1478 122 - 95 72 81 89 99 - 108 62 108 99 110 101 62 14 105 44 89 18 S72 RGFPLGLS AKSGGGP 1 8 8 - - - - - - - - - - - - - - - - - - - S81 KSGGGPGS GPRRTSS 1 20 - - - - - - - - - - 10 10 - - - - - - - - S87 GSGPRRTS SEELRDA 9 461 9 - - - 43 38 73 - 24 13 5 4 28 25 68 16 28 13 60 14 S88 SGPRRTSS EELRDAT 10 566 7 - 22 20 49 49 27 - 48 31 34 32 49 43 78 16 17 7 24 13
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S43 GAVQGAGS LGPGSPV - - - - - - - - - - - S48 AGSLGPGS PVRAGAS 1.9e-9 - 0.16 -0.53 - 0.18 1.0e-6 7.5e-5 -0.47 4.5e-3 9.8e-5 S55 SPVRAGAS IPSSGAA - - - - - - - - - - - S58 RAGASIPS SGAASPR - - - - - - - - - - - S59 AGASIPSS GAASPRG -0.12 - - - - -0.12 - - - - - S63 IPSSGAAS PRGFPLG 2.2e-3 - 1 -6.8e-4 - 0.025 1.4e-7 1.4e-14 -0.46 -1.5e-9 2.6e-4 S72 RGFPLGLS AKSGGGP - - - - - - - - - - - S81 KSGGGPGS GPRRTSS - - - - - - - - - - - S87 GSGPRRTS SEELRDA -0.87 - - -0.15 - 0.016 - 0.53 0.28 0.062 -3.8e-5 S88 SGPRRTSS EELRDAT -0.043 - 8.1e-3 0.84 - -0.23 -1.1e-7 -0.005 0.68 - 0.48
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S43
S48
S55
S58
S59
S63
S72
S81
S87
S88
T95
S96
Y132
S133
S134
T140
S147
S160
S201
S205
S214
S234
S247
S250
S251
S254
S257
S259
T297
S298
S301
S302
S304
T313
S315
S323
Y336
S343
S345
S349
S353
S357
S361
S366
S377
S383
S391
T397
S413
S421
S431
S433
S435
S456
S462
S467
S540
S570
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation CCRCC S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation COAD S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation GBM S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation HNSCC S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation LSCC S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation LUAD S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation OV S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation PDAC S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation UCEC S43 S48 S55 S58 S59 S63 S72 S81 S87 S88 T95 S96 Y132 S133 S134 T140 S147 S160 S201 S205 S214 S234 S247 S250 S251 S254 S257 S259 T297 S298 S301 S302 S304 T313 S315 S323 Y336 S343 S345 S349 S353 S357 S361 S366 S377 S383 S391 T397 S413 S421 S431 S433 S435 S456 S462 S467 S540 S570 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S43
S48
S55
S58
S59
S63
S72
S81
S87
S88
T95
S96
Y132
S133
S134
T140
S147
S160
S201
S205
S214
S234
S247
S250
S251
S254
S257
S259
T297
S298
S301
S302
S304
T313
S315
S323
Y336
S343
S345
S349
S353
S357
S361
S366
S377
S383
S391
T397
S413
S421
S431
S433
S435
S456
S462
S467
S540
S570
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S43
S48
S55
S58
S59
S63
S72
S81
S87
S88
T95
S96
Y132
S133
S134
T140
S147
S160
S201
S205
S214
S234
S247
S250
S251
S254
S257
S259
T297
S298
S301
S302
S304
T313
S315
S323
Y336
S343
S345
S349
S353
S357
S361
S366
S377
S383
S391
T397
S413
S421
S431
S433
S435
S456
S462
S467
S540
S570
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.