Protein: ENSP00000264335
Gene: YWHAE

LinkedOmicsKB © 2022-2023 Zhang Lab

YWHAE:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S64RASWRIISSIEQKEE16------------------6-
S65ASWRIISSIEQKEEN63297-4224--72-3924--1816--6027--
T114HLIPAANTGESKVFY388--8---71-----54------
S117PAANTGESKVFYYKM447------9-53------12612-
Y131MKGDYHRYLAEFATG62479-2812--99-4429--9872----
T137RYLAEFATGNDRKEA172------72-------------
T208DAIAELDTLSEESYK516952-3720----441091716------
S210IAELDTLSEESYKDS9713--1212808181-62391081716388100428918
S213LDTLSEESYKDSTLI263------54-63----------
T232RDNLTLWTSDMQGDG110----------55--------
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S64RASWRIISSIEQKEE-----------
S65ASWRIISSIEQKEEN-6.6e-15--7.5e-3---5.2e-5----1.2e-11-
T114HLIPAANTGESKVFY-----------
S117PAANTGESKVFYYKM-----------
Y131MKGDYHRYLAEFATG-1.3e-3--0.83---1.4e-5-----
T137RYLAEFATGNDRKEA-----------
T208DAIAELDTLSEESYK0.14-0.14--------
S210IAELDTLSEESYKDS-1.9e-16---1.4e-10--9.2e-5----9.6e-9-0.69
S213LDTLSEESYKDSTLI-----------
T232RDNLTLWTSDMQGDG-----------
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationCCRCCS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationCOADS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationGBMS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationHNSCCS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationLSCCS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationLUADS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationOVS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationPDACS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylationUCECS64S65T114S117Y131T137T208S210S213T232S233proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.