SUB1:
SUB1 regulator of transcription

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S9PKSKELVSSSSSGSD71449---12636-126--5471--397
S10KSKELVSSSSSGSDS103097-447272-17840365418632659
S11SKELVSSSSSGSDSD913225-88729-5255108--13520-
S12KELVSSSSSGSDSDS1046947-12127172-261654514440101447718
S13ELVSSSSSGSDSDSE925948-87161128---545547428412-
S15VSSSSSGSDSDSEVD942114-3432211562-201354444037--52262
S17SSSSGSDSDSEVDKK101047105-8780484281-673954464845471198428918
S19SSGSDSDSEVDKKLK1061540-88868380-1173938108321035148818
S46KQKTGETSRALSSSK12525-------------------
S50GETSRALSSSKQSSS331----72----------7213-
Showing 1 to 10 of 19 rows
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S9PKSKELVSSSSSGSD-----------
S10KSKELVSSSSSGSDS4.9e-13-----4.9e-13----
S11SKELVSSSSSGSDSD-----------
S12KELVSSSSSGSDSDS9.4e-21----2.3e-62.2e-13-0.02-1.7e-5
S13ELVSSSSSGSDSDSE7.5e-4------7.5e-4---
S15VSSSSSGSDSDSEVD3.5e-13--0.010.003-3.5e-92.8e-102.6e-4---
S17SSSSGSDSDSEVDKK7.9e-22--5.8e-33.5e-5-1.4e-74.8e-131.6e-150.60.748.5e-6
S19SSGSDSDSEVDKKLK5.8e-19--3.7e-16--1.2e-7-0.16-0.871.8e-7
S46KQKTGETSRALSSSK-----------
S50GETSRALSSSKQSSS-----------
Showing 1 to 10 of 19 rows
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationCCRCCS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationCOADS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationGBMS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationHNSCCS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationLSCCS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationLUADS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationOVS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationPDACS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylationUCECS9S10S11S12S13S15S17S19S46S50S51S52S55S56S57S58S104S111S118proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.