ANLN: anillin actin binding protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2y7b chain A
4xh3 chain A
4xoi chain B
4xoi chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S54 ASNQQPLS GGEEKSC 10 567 96 - 12 12 12 15 35 - 92 51 88 82 5 4 7 1 18 8 16 13 S65 EKSCTKPS PSKKRCS 10 1255 113 - 40 40 80 72 90 - 102 58 103 81 105 87 62 14 85 35 73 15 S72 SPSKKRCS DNTEVEV 8 225 35 - - - - - 18 - 12 7 15 13 4 4 14 2 33 13 48 7 T75 KKRCSDNT EVEVSNL 2 16 - - - - - - - - - - 5 5 - - - - - - 6 - S97 STSAKSCS PSPVSPQ 8 217 33 - 4 4 13 14 - - 12 6 42 39 17 17 - - 7 2 5 2 S99 SAKSCSPS PVSPQVQ 5 122 48 - - - - - - - 5 4 22 19 9 8 - - 5 2 - - S102 SCSPSPVS PQVQPQA 9 393 97 - 16 16 9 9 - - 62 35 30 23 33 27 4 - 10 5 6 11 T112 VQPQAADT ISDSVAV 2 17 - - 4 4 - - - - - - 5 4 - - - - - - - - S141 LEATAASS VKTRMQK 2 65 47 - - - - - - - - - 9 9 - - - - - - - - S182 PSEEKAAS PPRPLLS 10 1247 112 - 33 31 82 87 55 - 108 62 103 91 89 79 73 18 85 33 89 17
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S54 ASNQQPLS GGEEKSC 2.2e-6 - - - - -0.14 3.1e-16 - - - - S65 EKSCTKPS PSKKRCS 1.8e-77 - 1.0e-4 2.1e-15 - 3.5e-15 1.9e-28 1.3e-23 1.1e-3 7.4e-13 0.14 S72 SPSKKRCS DNTEVEV 0.002 - - - - - - - - 0.002 - T75 KKRCSDNT EVEVSNL - - - - - - - - - - - S97 STSAKSCS PSPVSPQ 0.96 - - - - - 0.96 - - - - S99 SAKSCSPS PVSPQVQ 0.87 - - - - - 0.87 - - - - S102 SCSPSPVS PQVQPQA -0.021 - - - - -2.2e-10 0.037 0.79 - - - T112 VQPQAADT ISDSVAV - - - - - - - - - - - S141 LEATAASS VKTRMQK - - - - - - - - - - - S182 PSEEKAAS PPRPLLS 1.1e-14 - 3.5e-4 0.066 - 2.6e-4 7.3e-6 5.3e-5 0.025 0.24 0.38
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S54
S65
S72
T75
S97
S99
S102
T112
S141
S182
S189
S192
T194
S225
S245
S252
S276
S281
S290
S295
S299
T320
S323
S336
S339
T364
S388
T397
T401
S419
S449
S471
T472
S485
S517
S518
S536
S553
S561
S562
S637
S639
S642
S658
S661
S664
S678
S688
S792
S795
S927
T1055
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation CCRCC S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation COAD S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation GBM S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation HNSCC S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation LSCC S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation LUAD S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation OV S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation PDAC S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation UCEC S54 S65 S72 T75 S97 S99 S102 T112 S141 S182 S189 S192 T194 S225 S245 S252 S276 S281 S290 S295 S299 T320 S323 S336 S339 T364 S388 T397 T401 S419 S449 S471 T472 S485 S517 S518 S536 S553 S561 S562 S637 S639 S642 S658 S661 S664 S678 S688 S792 S795 S927 T1055 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S54
S65
S72
T75
S97
S99
S102
T112
S141
S182
S189
S192
T194
S225
S245
S252
S276
S281
S290
S295
S299
T320
S323
S336
S339
T364
S388
T397
T401
S419
S449
S471
T472
S485
S517
S518
S536
S553
S561
S562
S637
S639
S642
S658
S661
S664
S678
S688
S792
S795
S927
T1055
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S54
S65
S72
T75
S97
S99
S102
T112
S141
S182
S189
S192
T194
S225
S245
S252
S276
S281
S290
S295
S299
T320
S323
S336
S339
T364
S388
T397
T401
S419
S449
S471
T472
S485
S517
S518
S536
S553
S561
S562
S637
S639
S642
S658
S661
S664
S678
S688
S792
S795
S927
T1055
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.