Protein: ENSP00000265753
Gene: EIF4H

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF4H:
eukaryotic translation initiation factor 4H

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S13TYDDRAYSSFGGGRG81988-44810--632322363129653--
S14YDDRAYSSFGGGRGS101192106-10380615671-92528879106971438837527
S21SFGGGRGSRGSAGGH101435122-9977919763-108621089995896116105448118
S24GGRGSRGSAGGHGSR953117-31315264-1025834295143346177--
S32AGGHGSRSQKELPTE19----36--------------
S69FKDLSIRSVRLVRDK265--3717------------74--
Y86DKFKGFCYVEFDEVD5607-----27-445544------
S94VEFDEVDSLKEALTY638449-3228--53---54495349----152
S110GALLGDRSLRVDIAE869439-5948--72-361873687973--4717569
S141DDRGMGSSRESRGGW25125-----26-------------
Showing 1 to 10 of 18 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S13TYDDRAYSSFGGGRG0.01------0.851.3e-4---
S14YDDRAYSSFGGGRGS6.3e-8-0.026-1.3e-6-5.2e-181.5e-57.8e-5--0.29-
S21SFGGGRGSRGSAGGH-7.3e-9-0.15-1.4e-17-4.3e-6-5.7e-8-0.0310.096-1.4e-4-3.7e-5
S24GGRGSRGSAGGHGSR8.4e-4-0.042--1.8e-4-0.820.26---
S32AGGHGSRSQKELPTE-----------
S69FKDLSIRSVRLVRDK0.51-0.51--------
Y86DKFKGFCYVEFDEVD-----------
S94VEFDEVDSLKEALTY1.2e-12-0.077---1.5e-55.6e-10---
S110GALLGDRSLRVDIAE2.5e-4-4.2e-8--0.820.281-0.6-
S141DDRGMGSSRESRGGW-----------
Showing 1 to 10 of 18 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationCCRCCS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationCOADS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationGBMS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationHNSCCS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationLSCCS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationLUADS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationOVS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationPDACS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylationUCECS13S14S21S24S32S69Y86S94S110S141S144S150T176S182S193T217T220S230proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.