Protein: ENSP00000265960
Gene: MAPKAP1

LinkedOmicsKB © 2022-2023 Zhang Lab

MAPKAP1:
MAPK associated protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T86GIRRRSNTAQRLERL11515-------------------
S116KERNSKQSAQELKSL6113--88--9---10854--32479
S185DVYLPLHSSQDRLLP613234-3324729-----8771----
S186VYLPLHSSQDRLLPM107069-3827181828-62396964373235898416716
S250TDFPPLDSNEPIHKF4426-43----12854--------
S270ALVEKYSSPGLTSKE838617-77--72-231450471817--258729
S290INAAHGFSLIQVDNT114--113----------------
Y323QKVSGPQYRLEKQSE379------9-------295--342
S367DGVFEEDSQIDIATV166-------------------
S510RKLNRRTSFSFQKEK10127646-21209710099-87509891106978319105449518
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T86GIRRRSNTAQRLERL-----------
S116KERNSKQSAQELKSL-----------
S185DVYLPLHSSQDRLLP-1.4e-10--1.4e-10--------
S186VYLPLHSSQDRLLPM-2.7e-3--1.1e-6--0.310.53-0.59--2.6e-80.046
S250TDFPPLDSNEPIHKF-----------
S270ALVEKYSSPGLTSKE1.6e-8----1.1e-32.3e-6----
S290INAAHGFSLIQVDNT-----------
Y323QKVSGPQYRLEKQSE-----------
S367DGVFEEDSQIDIATV-----------
S510RKLNRRTSFSFQKEK0.63--6.5e-3-2.3e-4-2.1e-6-9.6e-50.42.8e-52.1e-10-8.5e-6
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationCCRCCT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationCOADT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationGBMT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationHNSCCT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationLSCCT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationLUADT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationOVT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationPDACT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylationUCECT86S116S185S186S250S270S290Y323S367S510S512proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.