GTF2H1: general transcription factor IIH subunit 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1pfj chain A
2dii chain A
2rnr chain B
2ruk chain B
2rvb chain B
5gow chain B
5xv8 chain B
6nmi chain C
6o9l chain 1
6o9m chain 1
7ad8 chain I
7bul chain A
7egb chain 1
7egc chain 1
7ena chain 1
7enc chain 1
7lbm chain Y
7nvr chain 1
7nvw chain 1
7nvx chain 1
7nvy chain 1
7nvz chain 1
7nw0 chain 1
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S339 PSNMDGNS GDADCFQ 5 62 15 - 4 4 5 4 - - - - 5 4 - - - - - - 17 4 S357 KRAKLQES IEYEDLG 1 6 - - - - - - - - - - - - - - - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S339 PSNMDGNS GDADCFQ - - - - - - - - - - - S357 KRAKLQES IEYEDLG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S339
S357
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S339 S357 protein RNA SCNV methylation CCRCC S339 S357 protein RNA SCNV methylation COAD S339 S357 protein RNA SCNV methylation GBM S339 S357 protein RNA SCNV methylation HNSCC S339 S357 protein RNA SCNV methylation LSCC S339 S357 protein RNA SCNV methylation LUAD S339 S357 protein RNA SCNV methylation OV S339 S357 protein RNA SCNV methylation PDAC S339 S357 protein RNA SCNV methylation UCEC S339 S357 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S339
S357
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S339
S357
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.