EIF2B2: eukaryotic translation initiation factor 2B subunit beta
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6caj chain C
6caj chain D
6ezo chain C
6ezo chain D
6k71 chain C
6k71 chain D
6k72 chain C
6k72 chain D
6o81 chain C
6o81 chain D
6o85 chain C
6o85 chain D
6o9z chain C
6o9z chain D
7d43 chain C
7d43 chain D
7d44 chain C
7d44 chain D
7d45 chain C
7d45 chain D
7d46 chain C
7d46 chain D
7f64 chain C
7f64 chain D
7f66 chain C
7f66 chain D
7f67 chain C
7f67 chain D
7kmf chain C
7kmf chain D
7l70 chain C
7l70 chain D
7l7g chain C
7l7g chain D
7rlo chain C
7rlo chain D
7trj chain C
7trj chain D
7vlk chain C
7vlk chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S103 LHGRSDES DQQESLH 8 319 30 - 9 8 21 15 18 - 34 18 33 30 51 44 7 1 - - - - S108 DESDQQES LHKLLTS 3 36 - - - - - - - - 12 7 5 4 - - 7 1 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S103 LHGRSDES DQQESLH -0.01 - - 0.53 - 0.18 -1.5e-3 -8.0e-5 - - - S108 DESDQQES LHKLLTS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S103
S108
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S103 S108 protein RNA SCNV methylation CCRCC S103 S108 protein RNA SCNV methylation COAD S103 S108 protein RNA SCNV methylation GBM S103 S108 protein RNA SCNV methylation HNSCC S103 S108 protein RNA SCNV methylation LSCC S103 S108 protein RNA SCNV methylation LUAD S103 S108 protein RNA SCNV methylation OV S103 S108 protein RNA SCNV methylation PDAC S103 S108 protein RNA SCNV methylation UCEC S103 S108 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S103
S108
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S103
S108
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.