PML: PML nuclear body scaffold
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1bor chain A
2mvw chain A
2mvw chain B
2mwx chain A
4wjn chain B
4wjo chain B
5yuf chain A
5yuf chain B
5yuf chain C
5yuf chain D
6imq chain A
6imq chain B
6imq chain C
6imq chain D
6uyo chain B
6uyo chain D
6uyp chain B
6uyq chain B
6uyr chain B
6uys chain B
6uys chain D
6uyt chain B
6uyu chain B
6uyu chain D
6uyv chain B
8dji chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S8 MEPAPARS PRPQQDP 7 503 - - 4 4 - - 18 - 18 9 88 79 77 73 - - 30 12 82 9 T22 PARPQEPT MPPPETP 1 16 - - - - - - - - - - - - 9 7 - - - - - - T28 PTMPPPET PSEGRQP 2 44 - - - - - - - - - - 5 5 18 16 - - - - - - S30 MPPPETPS EGRQPSP 4 34 - - - - - - - - - - 5 5 5 4 - - 6 3 6 - S36 PSEGRQPS PSPSPTE 7 562 - - 38 26 - - 45 - 30 16 63 59 83 76 - - 25 11 72 18 S38 EGRQPSPS PSPTERA 7 641 - - 25 23 - - 72 - 77 46 64 59 44 40 - - 86 35 59 11 S40 RQPSPSPS PTERAPA 7 768 - - 28 27 - - 91 - 81 45 88 79 63 57 - - 74 28 89 18 T42 PSPSPSPT ERAPASE 3 44 - - 4 4 - - - - - - 10 9 9 8 - - - - - - S48 PTERAPAS EEEFQFL 6 367 - - - - - - 9 - 61 35 93 85 5 4 - - 8 4 54 9 T196 CSNPNHRT PTLTSIY 6 430 - - - - - - 78 - 68 40 30 28 22 19 - - 54 21 63 7
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S8 MEPAPARS PRPQQDP 0.2 - - - - - -0.96 0.056 - 0.73 - T22 PARPQEPT MPPPETP - - - - - - - - - - - T28 PTMPPPET PSEGRQP - - - - - - - - - - - S30 MPPPETPS EGRQPSP - - - - - - - - - - - S36 PSEGRQPS PSPSPTE 3e-15 - 5.3e-10 - - 3.0e-5 1.3e-8 -0.18 - 0.81 1.2e-5 S38 EGRQPSPS PSPTERA 6.6e-15 - 2.3e-5 - - 7.2e-18 2.6e-12 0.77 - -0.024 0.23 S40 RQPSPSPS PTERAPA 6.7e-31 - 0.3 - - 1.7e-9 4.5e-23 3.5e-3 - 5.2e-4 6.5e-7 T42 PSPSPSPT ERAPASE - - - - - - - - - - - S48 PTERAPAS EEEFQFL 6.6e-7 - - - - 0.01 8.3e-6 - - - - T196 CSNPNHRT PTLTSIY 1.5e-13 - - - - 1.7e-10 0.027 7.7e-4 - 4.9e-3 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S8
T22
T28
S30
S36
S38
S40
T42
S48
T196
S221
S403
S408
T409
S463
Y464
S469
S480
S493
S504
S505
S512
T513
S514
S518
S527
S530
S535
S542
S560
S561
S562
S565
S570
S578
S579
S580
S582
S583
T867
S882
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation CCRCC S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation COAD S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation GBM S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation HNSCC S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation LSCC S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation LUAD S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation OV S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation PDAC S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation UCEC S8 T22 T28 S30 S36 S38 S40 T42 S48 T196 S221 S403 S408 T409 S463 Y464 S469 S480 S493 S504 S505 S512 T513 S514 S518 S527 S530 S535 S542 S560 S561 S562 S565 S570 S578 S579 S580 S582 S583 T867 S882 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S8
T22
T28
S30
S36
S38
S40
T42
S48
T196
S221
S403
S408
T409
S463
Y464
S469
S480
S493
S504
S505
S512
T513
S514
S518
S527
S530
S535
S542
S560
S561
S562
S565
S570
S578
S579
S580
S582
S583
T867
S882
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S8
T22
T28
S30
S36
S38
S40
T42
S48
T196
S221
S403
S408
T409
S463
Y464
S469
S480
S493
S504
S505
S512
T513
S514
S518
S527
S530
S535
S542
S560
S561
S562
S565
S570
S578
S579
S580
S582
S583
T867
S882
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.