Protein: ENSP00000269385
Gene: CBX8

LinkedOmicsKB © 2022-2023 Zhang Lab

CBX8:
chromobox 8

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S110RIPYPGRSPQDLAST9687113-2020222353-85487871--50101165918
S130GLRNMGLSPPASSTS24126-----------------105
S183RERERGTSRVDDKPS18--8-----------------
S190SRVDDKPSSPGDSSK612517---1521--126--44--191017-
S191RVDDKPSSPGDSSKK1067289-1312323154-12745411019343940152411
S195KPSSPGDSSKKRGPK18------------44------
S196PSSPGDSSKKRGPKP19------------------72
T234KGRKLDDTPSGAGKF3229----------15147063----607
S256QLARRQDSDLVQCGV1074732-2524585899-43233532262413496429518
T264DLVQCGVTSPSSAEA81139-4445----98446272387
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S110RIPYPGRSPQDLAST2.7e-14-4.7e-40.1-1.1e-41.6e-15-0.31-0.52
S130GLRNMGLSPPASSTS-----------
S183RERERGTSRVDDKPS-----------
S190SRVDDKPSSPGDSSK-----------
S191RVDDKPSSPGDSSKK5.6e-26--2.2e-11--3.3e-128.9e-26--7.4e-30.036
S195KPSSPGDSSKKRGPK-----------
S196PSSPGDSSKKRGPKP-----------
T234KGRKLDDTPSGAGKF7.8e-21------7.8e-21---
S256QLARRQDSDLVQCGV3.9e-10-1.0e-49.7e-4-1.5e-44.3e-102.1e-4--8.4e-4-0.3
T264DLVQCGVTSPSSAEA-----------
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationCCRCCS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationCOADS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationGBMS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationHNSCCS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationLSCCS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationLUADS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationOVS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationPDACS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylationUCECS110S130S183S190S191S195S196T234S256T264S265S311S332S352proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.