CEP131: centrosomal protein 131
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14 IGSVPERS PAGVDLS 4 98 38 - - - - - - - - - 20 19 - - 13 1 - - 7 - S21 SPAGVDLS LTGLPPP 1 18 18 - - - - - - - - - - - - - - - - - - - S35 PVSRRPGS AATTKPI 2 88 79 - - - - - - - 5 4 - - - - - - - - - - S47 KPIVRSVS VVTGSEQ 9 978 82 - 37 32 - - 90 - 91 53 88 81 40 35 77 17 100 42 95 18 S76 AINNLRRS NSTTQVS 1 4 - - - - - - - - - - - - - - - - 3 1 - - S78 NNLRRSNS TTQVSQP 9 1060 71 - 37 26 - - 96 - 100 56 98 90 66 61 82 18 103 43 95 18 S87 TQVSQPRS GSPRPTE 5 86 - - - - - - 9 - - - - - 13 12 7 2 5 2 27 9 S89 VSQPRSGS PRPTEPT 9 1205 114 - 83 70 - - 99 - 91 54 79 73 106 98 68 14 105 44 89 18 T93 RSGSPRPT EPTDFLM 1 4 - - - - - - - - - - - - - - - - - - 4 - T96 SPRPTEPT DFLMLFE 1 16 - - - - - - - - - - - - - - - - - - 12 4
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14 IGSVPERS PAGVDLS 0.27 - - - - - 0.27 - - - - S21 SPAGVDLS LTGLPPP - - - - - - - - - - - S35 PVSRRPGS AATTKPI - - - - - - - - - - - S47 KPIVRSVS VVTGSEQ 1e-18 - 5.9e-9 - - 1.3e-4 1.1e-15 2.1e-11 -0.097 0.44 -0.91 S76 AINNLRRS NSTTQVS - - - - - - - - - - - S78 NNLRRSNS TTQVSQP 8.4e-20 - 6.6e-3 - - 2.1e-5 7.3e-22 3.6e-20 0.024 -9.2e-10 0.029 S87 TQVSQPRS GSPRPTE - - - - - - - - - - - S89 VSQPRSGS PRPTEPT 3.6e-16 - 0.91 - - -0.98 1.5e-15 2.7e-13 0.02 -0.71 2.3e-5 T93 RSGSPRPT EPTDFLM - - - - - - - - - - - T96 SPRPTEPT DFLMLFE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S14
S21
S35
S47
S76
S78
S87
S89
T93
T96
S105
S114
S116
T117
S120
T137
S144
S146
S150
S208
S221
S239
S247
S308
S381
S414
S416
S417
S447
S450
S453
T493
S498
S499
T522
S525
S531
S534
S542
S549
S731
S745
S798
S1053
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation CCRCC S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation COAD S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation GBM S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation HNSCC S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation LSCC S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation LUAD S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation OV S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation PDAC S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation UCEC S14 S21 S35 S47 S76 S78 S87 S89 T93 T96 S105 S114 S116 T117 S120 T137 S144 S146 S150 S208 S221 S239 S247 S308 S381 S414 S416 S417 S447 S450 S453 T493 S498 S499 T522 S525 S531 S534 S542 S549 S731 S745 S798 S1053 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S14
S21
S35
S47
S76
S78
S87
S89
T93
T96
S105
S114
S116
T117
S120
T137
S144
S146
S150
S208
S221
S239
S247
S308
S381
S414
S416
S417
S447
S450
S453
T493
S498
S499
T522
S525
S531
S534
S542
S549
S731
S745
S798
S1053
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S14
S21
S35
S47
S76
S78
S87
S89
T93
T96
S105
S114
S116
T117
S120
T137
S144
S146
S150
S208
S221
S239
S247
S308
S381
S414
S416
S417
S447
S450
S453
T493
S498
S499
T522
S525
S531
S534
S542
S549
S731
S745
S798
S1053
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.