CELSR2: cadherin EGF LAG seven-pass G-type receptor 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y218 GEAGRLEY TMDALFD 1 8 - - 4 4 - - - - - - - - - - - - - - - - T219 EAGRLEYT MDALFDS 1 8 - - 4 4 - - - - - - - - - - - - - - - - S2629 LACSRKPS PDPALTT 1 16 - - - - - - - - - - - - - - 12 4 - - - - S2643 TKSTLTSS YNCPSPY 5 109 - - 3 3 - - 72 - 5 3 - - - - 7 1 - - 10 5 Y2644 KSTLTSSY NCPSPYA 1 8 - - 4 4 - - - - - - - - - - - - - - - - S2648 TSSYNCPS PYADGRL 8 775 71 - 67 52 - - 81 - 89 53 78 72 4 3 81 19 - - 87 18 S2662 LYQPYGDS AGSLHST 1 9 - - - - - - 9 - - - - - - - - - - - - - S2665 PYGDSAGS LHSTSRS 4 310 - - - - - - 54 - 103 59 - - - - 57 13 - - 18 6 S2668 DSAGSLHS TSRSGKS 3 76 8 - - - - - 54 - - - - - - - - - - - 12 2 S2670 AGSLHSTS RSGKSQP 1 8 - - - - - - - - - - - - - - 7 1 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y218 GEAGRLEY TMDALFD - - - - - - - - - - - T219 EAGRLEYT MDALFDS - - - - - - - - - - - S2629 LACSRKPS PDPALTT - - - - - - - - - - - S2643 TKSTLTSS YNCPSPY - - - - - - - - - - - Y2644 KSTLTSSY NCPSPYA - - - - - - - - - - - S2648 TSSYNCPS PYADGRL 4.3e-3 - -0.17 - - -0.012 5.9e-7 - 1.8e-4 - 0.12 S2662 LYQPYGDS AGSLHST - - - - - - - - - - - S2665 PYGDSAGS LHSTSRS 1.2e-3 - - - - 1.3e-4 - - 0.46 - - S2668 DSAGSLHS TSRSGKS - - - - - - - - - - - S2670 AGSLHSTS RSGKSQP - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y218
T219
S2629
S2643
Y2644
S2648
S2662
S2665
S2668
S2670
S2675
S2678
T2777
S2819
S2823
S2848
T2862
S2864
S2865
S2868
S2869
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation CCRCC Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation COAD Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation GBM Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation HNSCC Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation LSCC Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation LUAD Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation OV Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation PDAC Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation UCEC Y218 T219 S2629 S2643 Y2644 S2648 S2662 S2665 S2668 S2670 S2675 S2678 T2777 S2819 S2823 S2848 T2862 S2864 S2865 S2868 S2869 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y218
T219
S2629
S2643
Y2644
S2648
S2662
S2665
S2668
S2670
S2675
S2678
T2777
S2819
S2823
S2848
T2862
S2864
S2865
S2868
S2869
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y218
T219
S2629
S2643
Y2644
S2648
S2662
S2665
S2668
S2670
S2675
S2678
T2777
S2819
S2823
S2848
T2862
S2864
S2865
S2868
S2869
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.