FAM120A: family with sequence similarity 120A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S30 LQKLARGS LVGGGRQ 10 1039 105 - 33 31 20 24 63 - 77 47 108 99 70 64 53 14 97 42 77 15 T42 GRQRPPQT PLRLLVD 1 9 - - - - - - - - - - - - 5 4 - - - - - - S312 DVFQHSQS RTDDKVI 3 39 6 - 13 11 - - - - - - 5 4 - - - - - - - - S435 TPLYERSS PINPAQS 6 189 26 - - - 10 16 89 - 6 3 - - - - 25 8 - - 6 - S442 SPINPAQS GSPNHVD 5 77 6 - - - 6 3 46 - 5 3 - - - - 7 1 - - - - S444 INPAQSGS PNHVDSA 5 87 16 - - - 5 3 45 - 6 3 - - - - - - - - 7 2 S456 DSAYFPGS STSSSSD 2 16 - - - - - - 7 - 6 3 - - - - - - - - - - T458 AYFPGSST SSSSDND 1 8 - - - - - - 8 - - - - - - - - - - - - - S462 GSSTSSSS DNDEGSG 1 44 - - - - - - 44 - - - - - - - - - - - - - T472 DEGSGGAT NHISGNK 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S30 LQKLARGS LVGGGRQ -1.2e-5 - 4.7e-3 -0.041 - 7.1e-9 -3.2e-4 -3.1e-9 -0.07 -1.8e-8 -0.045 T42 GRQRPPQT PLRLLVD - - - - - - - - - - - S312 DVFQHSQS RTDDKVI - - - - - - - - - - - S435 TPLYERSS PINPAQS - - - - - - - - - - - S442 SPINPAQS GSPNHVD - - - - - - - - - - - S444 INPAQSGS PNHVDSA - - - - - - - - - - - S456 DSAYFPGS STSSSSD - - - - - - - - - - - T458 AYFPGSST SSSSDND - - - - - - - - - - - S462 GSSTSSSS DNDEGSG - - - - - - - - - - - T472 DEGSGGAT NHISGNK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S30
T42
S312
S435
S442
S444
S456
T458
S462
T472
S487
S489
S506
S507
T508
S510
S511
S513
T525
T545
S652
T655
S852
T854
S916
S923
S925
S927
S933
S942
S960
T991
Y1020
S1023
S1040
S1041
S1044
S1045
S1048
S1067
S1075
S1077
S1079
T1090
S1098
T1099
S1101
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation CCRCC S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation COAD S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation GBM S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation HNSCC S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation LSCC S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation LUAD S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation OV S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation PDAC S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation UCEC S30 T42 S312 S435 S442 S444 S456 T458 S462 T472 S487 S489 S506 S507 T508 S510 S511 S513 T525 T545 S652 T655 S852 T854 S916 S923 S925 S927 S933 S942 S960 T991 Y1020 S1023 S1040 S1041 S1044 S1045 S1048 S1067 S1075 S1077 S1079 T1090 S1098 T1099 S1101 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S30
T42
S312
S435
S442
S444
S456
T458
S462
T472
S487
S489
S506
S507
T508
S510
S511
S513
T525
T545
S652
T655
S852
T854
S916
S923
S925
S927
S933
S942
S960
T991
Y1020
S1023
S1040
S1041
S1044
S1045
S1048
S1067
S1075
S1077
S1079
T1090
S1098
T1099
S1101
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S30
T42
S312
S435
S442
S444
S456
T458
S462
T472
S487
S489
S506
S507
T508
S510
S511
S513
T525
T545
S652
T655
S852
T854
S916
S923
S925
S927
S933
S942
S960
T991
Y1020
S1023
S1040
S1041
S1044
S1045
S1048
S1067
S1075
S1077
S1079
T1090
S1098
T1099
S1101
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.