Protein: ENSP00000277570
Gene: PROSER2

LinkedOmicsKB © 2022-2023 Zhang Lab

PROSER2:
proline and serine rich 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S8MPVTHRKSDASDMNS5325--------37261514--36660248918
S11THRKSDASDMNSDTS3618---------2423------6-
S15SDASDMNSDTSPSCR416739-2012------34291815------
T17ASDMNSDTSPSCRLR716339---1619--6420189861--134
S18SDMNSDTSPSCRLRA974738-17144850--674065594539711746189518
S27SCRLRAFSRGGSLES120--------128----------
S31RAFSRGGSLESRSSS1094715-88636245-63381049582734811100427218
S41SRSSSSRSRSFTLDD438--88----53--44----6-
S43SSSSRSRSFTLDDES9100163-58451016--10862999156528319102427718
T45SSRSRSFTLDDESLK835726-214----1410847798142327013
Showing 1 to 10 of 24 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S8MPVTHRKSDASDMNS2.6e-12----2.1e-5---3.0e-61.4e-3
S11THRKSDASDMNSDTS0.18-----0.18----
S15SDASDMNSDTSPSCR-0.78--7.6e-4---2.9e-3----
T17ASDMNSDTSPSCRLR-0.57------0.57----
S18SDMNSDTSPSCRLRA8.1e-15--2.1e-6-2.1e-38.8e-40.0590.820.146e-9
S27SCRLRAFSRGGSLES-----------
S31RAFSRGGSLESRSSS3.0e-4--2.7e-6--0.69-0.35-0.0680.131.7e-50.025
S41SRSSSSRSRSFTLDD-----------
S43SSSSRSRSFTLDDES-6.4e-6--0.02---0.36-2.2e-9-5.1e-120.1-0.784.7e-3
T45SSRSRSFTLDDESLK1.1e-4-----0.072---2.5e-4
Showing 1 to 10 of 24 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationCCRCCS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationCOADS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationGBMS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationHNSCCS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationLSCCS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationLUADS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationOVS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationPDACS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylationUCECS8S11S15T17S18S27S31S41S43T45S50T146T157S166T167S179S212T214S215S277S311S312S382S400proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.