Protein: ENSP00000280154
Gene: PDCD4

LinkedOmicsKB © 2022-2023 Zhang Lab

PDCD4:
programmed cell death 4

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S46EINGNWISASSINEA850066-1310----815145402929812477818
S48NGNWISASSINEARI6636-44----1285543--93--
S49GNWISASSINEARIN5193--------352010844--1167718
S67KRRLRKNSSRDSGRG869425-75681799-3519103948575----53
S68RRLRKNSSRDSGRGD1074440-4131818099-38235449221923676321911
S71RKNSSRDSGRGDSVS1063437-323172719-593139375653591142283
S76RDSGRGDSVSDSGSD101462122-95729710063-104581049510697831995399518
S78SGRGDSVSDSGSDAL7165--4454----39364429652167
S82DSVSDSGSDALRSGL226----810----44--------
S87SGSDALRSGLTVPTS19------9-------------
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S46EINGNWISASSINEA-0.35-----3.7e-120.0180.13--0.23
S48NGNWISASSINEARI-----------
S49GNWISASSINEARIN-1.3e-6-----3.0e-5-----7.5e-3
S67KRRLRKNSSRDSGRG-7.1e-18--0.51---9.8e-7-1e-18-4.5e-3---
S68RRLRKNSSRDSGRGD-2.9e-10--0.013-1.2e-7--1.5e-6-0.17-5.4e-3-0.2-
S71RKNSSRDSGRGDSVS-0.015--8.6e-4-8.9e-5--4.4e-42.5e-4-0.830.17--
S76RDSGRGDSVSDSGSD-2.8e-18--3.8e-3-4.1e-14--1.5e-17-8.6e-11-8.8e-3-0.0597.7e-60.39
S78SGRGDSVSDSGSDAL-0.015------0.015----
S82DSVSDSGSDALRSGL-----------
S87SGSDALRSGLTVPTS-----------
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationCCRCCS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationCOADS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationGBMS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationHNSCCS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationLSCCS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationLUADS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationOVS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationPDACS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylationUCECS46S48S49S67S68S71S76S78S82S87T90T93S94T126S313S317S323S345S422S457proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.